摘要
制备7种酸性低共熔溶剂(DES),在不同温度下系统测定低共熔溶剂的理化特性,评估了虾青素的溶解度,并与有机溶剂和离子液体进行比较,深入探讨虾青素溶解度与低共熔溶剂理化性质之间的关联性。结果表明,7种酸性低共熔溶剂具有低黏度和良好的热稳定性;虾青素在7种低共熔溶剂中的溶解效果均优于乙醇与离子液体三丁基辛基氯化膦,溶解能力最强的是DL-薄荷醇∶乙酸(MAA),可达(405.94±12.90)mg/100 g;低共熔溶剂的密度、黏度和偶极性/极化率3个性质与虾青素溶解能力密切相关,相关系数分别为0.99、-0.85和0.83,这为选择和设计提取天然类胡萝卜素的溶剂及其应用提供了理论指导。
7 Acidic deep eutectic solvents(DES)were prepared,and the effects of temperature on the physicochemical properties were explored.In addition,solubility of astaxanthin in different DES was measured and compared with organic solvent and ionic liquid(IL).Moreover,the correlation coefficients of the physicochemical properties and astaxanthin solubility were analyzed.The results showed that the acidic DES presented low viscosity and favourable thermal stability.The solubility of astaxanthin in all the DES was higher than that in ethanol and IL(tributyl(octyl)phosphonium chloride).Besides,DL-menthol∶acetic acid(MAA)showed the highest astaxanthin solubility of(405.94±12.90)mg/100 g.Furthermore,the correlation analysis showed that the astaxanthin solubility was significantly correlated with density,viscosity and dipolarity of DES,whose related coefficients are 0.99,-0.85 and 0.83 respectively.The study provides theoretical guidance for the pre-selection and design of suitable solvents for the extraction of carotenoids and their applications.
作者
程婉婷
陈世钰
贤凤
胡坤
高静
CHENG Wan-ting;CHEN Shi-yu;XIAN Feng;HU Kun;GAO Jing(Guangdong Pharmaceutical University,School of Public Health,Guangzhou 510000,China;Guangdong Pharmaceutical University,School of Food Science,Zhongshan 528400,China)
出处
《化学试剂》
CAS
北大核心
2023年第2期106-113,共8页
Chemical Reagents
基金
国家自然科学基金项目(21706040,22078070)
广东省自然科学基金项目(2019A15010640,2019A15011843)。
关键词
低共熔溶剂
理化性质
虾青素
溶解度
deep eutectic solvent
physicochemical properties
astaxanthin
solubility
