摘要
为更便捷高效地探究果蝇视网膜的神经计算机理,构建了果蝇复眼及视网膜的仿真系统。通过构建果蝇复眼光学结构与神经通路连接和视网膜神经元信息编码过程,模拟了光源到神经电信号的转化;通过统计学模型,优化了视网膜光电转化模型;通过仿真系统,探究了果蝇视网膜输出端神经元朝向选择性的发生机理。实验表明,在仿真效果精度相当下,仿真速度较业内已有平台提升近40倍,并可仅用单台笔记本替换高性能GPU实现仿真。提出果蝇视网膜朝向选择性在视神经系统第二层神经元就已出现的可能。
To investigate the biophysical mechanisms underlying the Drosophila retinal computations, a piece of simulation software is constructed. By constructing the connectivity of the optical structure of the Drosophila compound eye with the neural network and retinal neuronal information encoding processes,,the retinal transformation from the light to the electrical signals is simulated. The photo-transduction model is optimized by a stochastic process. The generating mechanism of orientation selectivity(OS) is explored in the Drosophila retina’s output neurons through a simulation system. Experiments show that with comparable simulation accuracy, the simulation speed increases by 40 times. The software can now be performed only on a single laptop without utilizing GPU clusters. The results show that the OS may already occur as early as in the second neural layer of Drosophila’s visual system.
作者
刘子钰
卓弋然
宋卓异
Liu Ziyu;Zhuo Yiran;Song Zhuoyi(Institute of Science and Technology for Brain-inspired Intelligence(ISTBI),Fudan University,Shanghai 200433,China;Research Institute of Intelligent Complex Systems,Fudan University,Shanghai 200433,China;MOE Frontiers Center for Brain Science,Fudan University,Shanghai 200032,China)
出处
《系统仿真学报》
CAS
CSCD
北大核心
2023年第1期123-136,共14页
Journal of System Simulation
基金
国家自然科学基金青年基金(12001111)
上海浦江人才计划(19PJ400800)
上海市“脑与类脑智能基础转化应用研究”市级科技重大专项(2018SHZDZX01)。
关键词
复眼
复眼光学系统
果蝇视网膜仿真系统
光感受器
朝向选择特性
compound eye
optical system of compound eye
Drosophila retina simulation system
photoreceptor
orientation selectivity(OS)
