摘要
目的:观察白驳酊治疗面部稳定期白癜风(阳虚血瘀型)的临床疗效及作用机制。方法:将符合纳入标准的120例面部稳定期阳虚血瘀型白癜风患者随机分为两组,治疗组和对照组,各60例。治疗组外涂自拟白驳酊,对照组外涂复方卡力孜然酊。两组均以治疗2个月为1个疗程,连续治疗4个月。分别于入组时、治疗2个月、治疗4个月记录并比较两组的白斑面积及DLQI评分,最后运用相应统计方法进行分析。结果:治疗2个月,两组白斑面积及DLQI评分与入组时组内比较,差异有统计学意义(P<0.05),组间比较差异亦有统计学意义(P<0.05);治疗4个月,两组白斑面积及DLQI评分与入组时、治疗2个月组内比较,差异有统计学意义(P<0.05),组间比较差异亦有统计学意义(P<0.05);治疗组总有效率为91.1%(51/56),对照组总有效率为81.8%(45/55)。两组临床有效率比较,差异有统计学意义(P<0.05)。结论:白驳酊治疗面部稳定期白癜风(阳虚血瘀型)有效且效果优于复方卡力孜然酊。
Objective:To observe the clinical efficacy and mechanism of Baibo Tincture in treatment of stable facial vitiligo(Yang deficiency and blood stasis type).Methods:A total of 120 patients with stable facial vitiligo of Yang deficiency and blood stasis syndrome were randomly divided into the treatment group and the control group,with 60 patients in each group.The treatment group was externally coated with self-made Baibo Tincture,and the control group was externally coated with compound Kali Ziran Tincture.The two groups were treated for two course of four months.The white patch area and the DLQI score were recorded and compared between the two groups before the treatment,after 2 months of the treatment and after 4 months of the treatment,and the data were finally analyzed by corresponding statistical methods.Results:There were statistical differences in the white patch area and the DLQI score between before the treatment and after 2 months of the treatment within the same group(P<0.05);in which there were also differences between the two groups after two months of the treatment(P<0.05).After 4 months of the treatment,the white patch area and the DLQI score were significantly different from those before the treatment and after 2 months of the treatment within the same group(P<0.05);in which there were also differences between the two groups(P<0.05).The total effective rate was 91.1%(51/56)in the treatment group,which was significantly higher than 81.8%(45/55)in the control group(P<0.05).Conclusion:Baibo Tincture is effective in treatment of stable facial vitiligo(Yang deficiency and blood stasis),and the effect is better than that of compound Kali Ziran Tincture.
作者
王远红
方殿伟
赵卫浩
WANG Yuanhong;FANG Dianwei;ZHAO Weihao(The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Heilongjiang University of Chinese Medicine,Harbin 150040,China;Xingtai Hospital of Traditional Chinese Medicine,Xingtai 054001,China)
出处
《中医药学报》
CAS
2023年第2期72-77,共6页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金面上项目(81873312)
黑龙江省自然科学基金面上项目(H201462)
哈尔滨市科技创新人才研究专项资金项目(2016RAXYJ102)。
关键词
白驳酊
稳定期
白癜风
阳虚血瘀
Baibo Tincture
Stable period
Vitiligo
Yang deficiency and blood stasis
