摘要
Visible-light-induced reductive dearomatization of nonactivated arenes is a very challenging transformation and remains in its infancy.Herein,we report a novel strategy to achieve a visible-light-induced spirocyclizative remote arylcarboxylation of nonactivated arenes including naphthalenyl-and phenyl-bearing aromatics with CO_(2) under mild conditions through a radical-polar crossover cascade(RPCC).This reductive dearomatization protocol rapidly delivers a broad range of spirocyclic and valuable carboxylic acid derivatives from readily accessible aromatic precursors with generally good regioselectivity and chemoselectivity.
基金
the financial support from NSFC(grant nos.21871257,22022111,and 21801240)
the Natural Science Foundation of Fujian Province(grant no.2020J02008)
the Strategic Priority Research Program of the Chinese Academy of Sciences(grant no.XDB20000000).
