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弱视眼底光学相干断层扫描的研究进展

Advances in Optical Coherence Tomography in Amblyopia
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摘要 弱视是由于视觉发育关键期内各种异常的视觉经验导致单眼或双眼最佳矫正远视力低于正常同龄儿童,而眼部无明显器质性病变。目前普遍观点认为,弱视的发病机理主要源于视皮层。近年来,光学相干断层扫描(OCT)作为一种先进的活体成像技术,促进了对视网膜形态结构的大量研究,同时也被应用到弱视的研究领域。陆续有不同的研究人员利用OCT发现弱视患者眼底视网膜、脉络膜等眼部结构存在改变。笔者将对弱视眼底OCT的研究进展做一综述。 Amblyopia is a developmental visual impairment caused by abnormal visual experience during a critical period,which results in lower best corrected visual acuity of one or both eyes than that of normal children of the corresponding age,without obvious organic lesions in the eye.It is generally believed that the pathogenesis of amblyopia is mainly located in the visual cortex.In recent years,optical coherence tomography(OCT)as an advanced in vivo imaging technology has encouraged a great deal of research on the morphological structure of retina,and has also been applied to the research field of amblyopia.Different research groups have successively reported the findings of structural changes in the retina and choroid in the amblyopic eye by OCT technology.Here we will review these new progresses.
作者 徐治成 史学锋 Zhicheng Xu;Xuefeng Shi(Clinical College of Ophthalmology of Tianjin Medical University,Tianjin Eye Hospital,Tianjin Eye Institute,Tianjin Key Laboratory of Ophthalmology and Visual Science,Tianjin 300020,China)
出处 《中华眼视光学与视觉科学杂志》 CAS CSCD 2022年第12期950-955,共6页 Chinese Journal Of Optometry Ophthalmology And Visual Science
基金 国家自然科学基金面上项目(81770956,81371049) 天津市杰出青年科学基金项目(17JCJQJC46000) 天津市卫生计生行业高层次人才选拔培养工程"津门医学英才"项目。
关键词 弱视 光学相干断层扫描 视网膜 脉络膜 结构 发病机制 amblyopia optical coherence tomography retina choroid structure pathogenesis
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