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心房颤动患者血栓形成机制的研究进展

Research progress in mechanism of thrombosis in patients with atrial fibrillation
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摘要 心房颤动是临床上最常见的心律失常,与卒中和血栓栓塞关系密切。心房颤动通过破坏生理止血机制而增加血栓形成风险,这一机制可通过魏尔啸(Virchow)的“血液成分异常”“血管壁异常”和“血液流动异常”三联征来解释。左心耳因其复杂的形态结构和特殊的功能特点,成为心房颤动患者血栓形成的主要部位。提高对心房颤动血栓形成的各种因素的认识,有助于更好地对心房颤动血栓形成风险进行危险分层,并提供及时有效的治疗。 Atrial fibrillation is the most common arrhythmia in clinical practice and is closely related to stroke and thromboembolism.Atrial fibrillation increases the risk of thrombosis by disrupting physiological haemostatic mechanisms that are understood by reference to Virchow′s triad of“abnormal blood constituents”“vessel wall abnormalities”and“abnormal blood flow”.Left atrial appendage is the main part of atrial fibrillation due to its complex morphological structure and special functional characteristics.A better understanding of the various factors of atrial fibrillation thrombosis contributes to a better stratification of the risk of atrial fibrillation thrombosis and its timely and effective treatment.
作者 霍家敏 李学文 HUO Jia-Min;LI Xue-Wen(Department of Cardiology,Third Clinical Hospital of Shanxi Medical University,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Taiyuan 030032,China)
出处 《中华老年多器官疾病杂志》 2022年第12期945-948,共4页 Chinese Journal of Multiple Organ Diseases in the Elderly
基金 国家自然科学基金(82170398)。
关键词 心房颤动 左心耳 Virchow三联征 血栓形成 atrial fibrillation left atrial appendage Virchow triad thrombosis
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