摘要
目的 采用ICDAS评价含氟牙膏用于3~4岁不同Cariostat龋态值儿童的防龋效果。方法 本研究为随机、对照、双盲设计、为期12个月以幼儿园为依托单位的临床试验研究。选择北京市密云区7所儿童在园刷牙的幼儿园。通过纳入排除标准选择进入试验的儿童,根据基线时儿童的Cariostat龋活跃性检测结果,分层随机分入试验组(1100 ppm含氟牙膏)、对照组(无氟牙膏)。受试儿童与检查者均不知道儿童分组情况。受试儿童在家长和老师的监督下使用分发的牙膏每天刷牙3次,每次刷牙2 min,并用计时器计时。12个月后,对两组儿童进行终期口腔健康检查。采用独立样本t检验及卡方检验比较儿童组间统计指标的差异。结果 由于疫情影响,终期检查推迟2个月。经过14个月产品使用后,在低龋态值儿童中,试验组全部龋及早期龋新生龋面均明显低于对照组(P <0.05)。对于中高龋态值组的儿童来说,试验组与对照组儿童无论是成洞龋还是早期龋新生龋均、龋面均的组间差异都没有统计学意义(P> 0.05)。结论 在14个月的研究期内,1100 ppm含氟牙膏对低龋态值的儿童具有良好的早期龋预防效果,但未观察到对低龋态值儿童成洞龋的防龋效果。在中高龋态值儿童中,未观察到1100 ppm含氟牙膏具有防龋效果。
Objective To evaluate the anticaries effect of fluoride toothpaste in children with different Cariostat values by ICDAS. Methods This was a 12-month randomized,controlled and double-blind clinical study based on kindergarten. Children aged 3-4 years old in the 7 kindergartens in Miyun District Beijing were recruited to the study. The children were selected on the basis of inclusion and exclusion criteria. According to the results of Cariostat caries activity test at baseline, all recruited children were stratified and randomly allocated into 2 groups. The children should brush their teeth three times a day under the supervision of kindergarten teachers after breakfast and lunch. All children needed to brush their teeth for 120 seconds each time with a timer. 12 months later, the 2 groups of children were given final oral health examination.Independent sample t-test and chi square test were used to compare the differences between the groups. Results Due to the influence of COVID-19, the final inspection was postponed for two months, and the final research period was 14 months. In the children with low Cariostat value, the mean increment d1-6mft and d1-2s scores was lower than that in the control group(P<0.05).Among the children with moderate and high Cariostat value, there was no significant difference between the two groups after 14 months(P > 0.05). Conclusions For children with low Cariostat value, 1100ppm fluoride toothpaste has good preventive effect on incipient caries.However, there is no significant anticaries effect of 1100ppm fluoride toothpaste on cavitated caries in children aged 3-4 years.
作者
陈心心
唐哲
王笑喆
荣文笙
CHEN Xin-xin;TANG Zhe;WANG Xiao-zhe;RONG Wen-sheng(Peking University School and Hospital of Stomatology Department of Preventive Dentistry,Beijing 100081,China)
出处
《北京口腔医学》
CAS
2022年第6期412-417,共6页
Beijing Journal of Stomatology
