摘要
目的探讨丙泊酚联合依托咪酯麻醉诱导对腹腔镜胆囊切除术患者血流动力学及炎症因子的影响。方法选取青海省藏医院2020年1月至2022年1月期间收治的80例腹腔镜胆囊切除术患者,按数字随机表法分为两组各40例。对照组麻醉诱导为丙泊酚,观察组麻醉诱导为丙泊酚联合依托咪酯。比较两组术中不同时间点血流动力学变化,检测两组患者炎症因子变化,评价麻醉用药不良反应。结果观察组患P者诱导后心率、平均动脉压高于对照组,差异有显著性(<0.05);观察组患者术后1d炎症指标水平低P于对照组,术后睁眼、拔管以及定向力恢复时间均短于对照组,差异均有显著性(<0.05)。两组患者麻P醉不良反应发生率无显著差异(>0.05)。结论丙泊酚联合依托咪酯麻醉诱导用于腹腔镜胆囊切除术,麻醉诱导效果良好,患者血流动力学稳定,安全性高。
Objective To investigate the effect of propofol combined with etomidate anesthesia induction on.Method hemodynamics and inflammatory factors in patients undergoing laparoscopic cholecystectomy 80 cases of laparoscopic cholecystectomy patients admitted to Qinghai Tibetan Hospital from January 2020 to January 2022.were selected and divided into two groups with 40 cases each according to the method of numerical random table The control group was anesthetized with propofol,and the observation group was anesthetized with propofol and.etomidate The hemodynamic changes at different time points during the operation were compared between the two groups,the changes of inflammatory factors were detected in the two groups,and the adverse reactions of anesthetic.Result drugs were evaluated After induction,the heart rate and mean arterial pressure in the observation group P were significantly higher than those in the control group(<0.05);the level of inflammatory indicators in the observation group was lower than that in the control group on thefirst day after operation,and the recovery time of eye opening,catheter removal and directional force was shorter than that in the control group,with significant P.differences(<0.05)There was no significant difference in the incidence of adverse reaction to anesthesia P.Conclusion between the two groups(>0.05)Propofol combined with etomidate anesthesia induction for laparoscopic cholecystectomy has good effect,stable hemodynamics and high safety.
作者
文成措
WEN Chengcuo(Anesthesiology Department of Qinghai Tibetan Hospital,Qinghai Xining 810007,China)
出处
《临床普外科电子杂志》
2022年第4期49-52,66,共5页
Journal of General Surgery for Clinicians(Electronic Version)
关键词
丙泊酚
依托咪酯
麻醉诱导
腹腔镜胆囊切除术
血流动力学
炎症因子
Propofol
Etomidate
Induction of anesthesia
Laparoscopic cholecystectomy
Hemodynamics
Inflammatory factors
