摘要
目的评估强脉冲光联合1565 nm非剥脱点阵激光对鱼尾纹的治疗效果及患者满意度。方法2018年8月至2020年1月,北京同仁医院眼科收集年龄30~55岁、具有外眦部静态鱼尾纹特征的女性患者60例,年龄30~55岁,平均42岁。患者面部按随机数字表分为3个组;A组一侧面部用强脉冲光治疗,另一侧用非剥脱点阵激光治疗;B组一侧用非剥脱点阵激光治疗,另一侧用强脉冲光治疗后即刻接受非剥脱点阵激光治疗;C组一侧用强脉冲光治疗,另一侧用强脉冲光治疗后即刻接受非剥脱点阵激光治疗。按照Seeman 4分分级法、皮肤含水量测试、主观客观评估、患者满意度评估术后效果。结果强脉冲光+非剥脱点阵激光联合治疗侧和非剥脱点阵激光单独治疗侧除皱有效率在30、60、90 d,两侧皱纹评分较治疗前差异有统计学意义(F=4.52,P<0.05;F=12.84,P<0.05),且两组间外眦部鱼尾纹Seeman评分60 d和90 d时差异有统计学意义(t=0.15,P<0.05;t=0.10,P<0.05)。评估患者90 d外眦部位肌肤纹理改善方面联合治疗侧优于单独使用非剥脱点阵激光(t=0.19,P<0.05)和强脉冲光治疗侧(t=0.10,P<0.05)。结论强脉冲光术后即刻联合非剥脱点阵激光对改善外眦部鱼尾纹的效果和满意度显著优于单独用非剥脱点阵激光和强脉冲光。
Objective To evaluate the efficacy and patients'satisfaction of the intense pulse light(IPL)and M22-Resur Fx non-ablative fractional laser(NAFL)for the treatment of lateral static crow's feet.Methods A prospective split-face,randomized,controlled study of 60 consecutive patients with lateral static crow's feet was performed.The patients aged 30 to 55 years,who were enrolled in the Department of Ophthalmology,Beijing Tongren Hospital,Capital Medical University from January 2018 to January 2020.The two sides of each patient's face were randomized to receive different treatment,and according to their treatment,the patients were divided into 3 groups with 20 cases each:Group A,in which 20 patients'one side face was treated with IPL,and other side was treated with NAFL;Group B,in which one side face was treated with IPL,and another side was treated with IPL immediately followed by NAFL;Group C,in which one side face was treated with NAFL,and another side was treated with IPL immediately followed by NAFL.The improvements including the water content of stratum corneum of skin and the patients'satisfaction,as well as the improvement of the lateral static crow's feet were evaluated.Results The IPL plus NAFL combined treatment group and the NAFL treatment group showed the effective rate of the improvement for lateral static crow's feet of patients on days 60 and 90 was statistically significant(P<0.05)compared with that before the treatment.And the improvement for lateral static crow's feet of patients on days 60 and 90 in combined treatment side was significantly different from either NAFL side(P<0.05).60 days and 90 days after treatment,the satisfaction of combined treatment side was significantly higher than that of either NAFL side or IPL side(P<0.05).Conclusions The treatment with an optimized IPL immediately followed by a NAFL is clinically superior to those with the NAFL or IPL alone for improving the lateral static crow's feet of patients.The satisfaction treated by NAFL combined with IPL is higher than using the N
作者
辛月
李冬梅
Xin Yue;Li Dongmei(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University/Beijing Ophthalmology&Visual Science Key Lab.,Beijing 100730,China)
出处
《中华医学美学美容杂志》
2022年第6期512-516,共5页
Chinese Journal of Medical Aesthetics and Cosmetology
基金
国家自然科学基金(82071005)
北京市医院管理中心儿科学科协同发展中心专项(XTCX201824)。
关键词
激光
强脉冲光治疗
疗效比较研究
非剥脱点阵激光
鱼尾纹
Lasers
Intense pulsed light therapy
Comparative effectiveness research
Non-ablative fractional laser
Crow's feet
