摘要
目的:探讨慢性肾衰竭(CRF)尿毒症患者采用高通量血液透析滤过治疗的临床效果。方法:选取2020年1月-2022年1月江华瑶族自治县民族中医院收治的CRF尿毒症患者80例为研究对象,根据随机数字表法分为对照组与观察组,各40例。对照组行低通量血液透析治疗,观察组行高通量血液透析治疗,比较两组患者临床效果、肾功能、生化指标、并发症发生率。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗后,两组患者肌酐和尿素氮水平均降低,观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者Hb、TP、ALB、K^(+)、Na^(+)、CI^(-)、24 h尿量水平均改善,差异有统计学意义(P<0.05)。结论:临床运用高通量血液透析滤过治疗CRF尿毒症患者,疗效显著,可改善患者生化指标及肾功能,安全性高。
Objective:To investigate the clinical effect of treatment with high-flux hemodialysis filtration in uremic patients with chronic renal failure(CRF).Methods:Eighty patients with CRF uremia admitted to the Jianghua Yao Nationality Autonomous County Ethnic Chinese Hospital from January 2020 to January 2022 were selected as study subjects and divided into control group and observation group according to the random number table method,with 40 cases each.The control group was treated with lowflux hemodialysis and the observation group was treated with high-flux hemodialysis,and the clinical effects,renal function,biochemical indexes,and complication rates of the two groups were compared.Results:The total efficiency of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the creatinine and urea nitrogen levels were reduced in both groups,and the difference was statistically significant(P<0.05)in the observation group than in the control group.After treatment,the levels of Hb,TP,ALB,K^(+),Na^(+),CI^(-),and 24-h urine volume improved in both groups,and the difference was statistically significant(P<0.05).Conclusion:The clinical use of highflux hemodialysis filtration for the treatment of uremic patients with CRF has significant efficacy and can improve the biochemical indexes and renal function of patients with high safety.
作者
唐丽
Tang Li(Jianghua Yao Nationality Autonomous County Ethnic Chinese Hospital,Yongzhou 425500,Hunan Province,China)
出处
《中外医药研究》
2022年第10期33-35,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
慢性肾衰竭
高通量血液透析
尿毒症
肾功能
Chronic renal failure
High-flux hemodialysis
Uremia
Renal function
