摘要
嗜酸细胞性胃肠炎(EGE)是一种以嗜酸性粒细胞(Eos)在胃肠道异常增高为主要特征的少见疾病,临床上容易漏诊及误诊。本文报道了1例内镜表现非典型的EGE患者诊疗经过,患者因反复腹痛2年,呕吐、腹泻1 d入院,在排除过敏性疾病、寄生虫感染等后,根据患者临床表现、外周血Eos升高及胃肠组织病理活检结果,诊断为EGE,予泼尼松治疗1个月后,患者症状完全缓解,血液学检验异常指标基本恢复正常,随访至截稿日期,患者未出现复发。通过此报道,以期加深临床医师对此病的认识,提高对此病尤其是对内镜表现非典型EGE的识别能力,为临床医师提供可参考的诊疗思路,减少漏诊及误诊。
Eosinophilic gastroenteritis(EGE)is a rare disease characterized by the dense eosinophil(Eos)infiltration of gastrointestinal tract.It is easily misdiagnosed and missed diagnosed.In this paper,the diagnosis and treatment of one case of EGE with atypical endoscopic features is reported.The patient was admitted to hospital due to the recurrent abdominal pain for 2 years and vomiting accompanied with diarrhea for 1 day.After ruling out the possibility of parasitic infection and allergic diseases,the patient was diagnosed with EGE based on the clinical manifestations,increased peripheral blood Eos,and gastrointestinal pathological result.After prednisone therapy for a month,the patient's symptoms basically disappeared and the laboratory blood tests returned to normal.As so far,the patient remained physically stable.This case provides the clinicians with the references to diagnose and treat EGE,so as to strengthen their understanding of this disease and improve their ability to identify EGE,especially those with atypical endoscopic features and to reduce the rate of misdiagnosis and missed diagnosis.
作者
欧阳晓佳
何琼
Ouyang Xiaojia;He Qiong(Department of Gastroenterology,First Hospital,Jinan University,Guangzhou 510630,China)
出处
《国际医药卫生导报》
2023年第2期228-231,共4页
International Medicine and Health Guidance News
基金
青年科学基金项目(81500420)
广东省自然科学基金项目(2015A030310114)。
关键词
嗜酸细胞性胃肠炎
诊断
治疗
Eosinophilic gastroenteritis
Diagnosis
Treatment