摘要
In a recent study published in Nature,Suryawanshi et al.showed that primary Omicron infection only elicits a mild humoral immune response and limited cross-variant neutralization in non-vaccinated individuals.1On the other hand,vaccinated individuals developed high neutralizing antibody titers against all variants of concern(VOCs)following breakthrough Omicron infections.Hence,Omicron infection can enhance existing immunity induced by vaccination but may not prevent reinfection by other VOCs in non-vaccinated individuals.
基金
H.M,L.H,and Q.P.H.are supported by the European Union's Horizon 2020 research and innovation program under grant agreement No 101003650(ATAC)
the Swedish Research Council,and the Knut and Alice Wallenberg Foundation(KAW).
