摘要
性激素受体在大脑神经元上广泛分布,研究表明,性激素对学习记忆能力有重要的促进作用且其效应存在潜在的性别差异。长时程增强是研究最深入的记忆细胞模型之一,在其各环节都显示了记忆编码的性双态现象。该文通过对比分析雌激素与雄激素在脑神经元、突触与胶质细胞中分别的作用机制,从性激素角度出发,综述了引起两性学习记忆能力差异的机制。
Sex hormone receptors are widely distributed in brain neurons.Studies have shown that sex hormones play the important promoting role on learning and memory capacities, moreover their effects have the potential gender divergence.The long-term potentiation is one of the most intensively studied memory cell models, in each link, it shows the sexual bimodal phenomenon of memory encoding.This paper reviews the mechanism causing the difference of learning and memory abilities between sexes from the perspective of sex hormones by comparatively analyzing the action mechanisms of estrogen and androgen respectively in brain neurons, synapses and glial cells.
作者
秦亚涵
潘盈佳(综述)
孙支唐(审校)
QIN Yahan;PAN Yingjia;SUN Zhitang(First Clinical Medical College of Shanxi Medical University,Taiyuan,Shanxi 030002,China;Department of Neurology,Second Hospital of Shanxi Medical University,Taiyuan,Shanxi 030002,China)
出处
《现代医药卫生》
2023年第1期122-127,共6页
Journal of Modern Medicine & Health
关键词
雌激素
雄激素
性别差异
学习记忆
综述
Estrogen
Androgen
Gender differences
Learning and memory
Review