摘要
目的分析非结节性甲状腺内微钙化的临床和超声表现,对照病理,探讨其与甲状腺乳头状癌的关系。方法选取无明确结节的甲状腺内微钙化患者24例,分析患者超声影像特征,包括钙化区域的大小、位置,根据钙化集聚程度,分为簇状微钙化组(A组)和散在微钙化组(B组)。所有患者均进行了细针抽吸活检。以病理结果为标准,分析不同年龄、性别、钙化集聚程度与甲状腺癌的关系。结果24例非结节性甲状腺内微钙化病例中,甲状腺乳头状癌15例,恶性率为62.5%,恶性患者平均年龄27.3岁,良性患者平均年龄39.1岁,2组年龄差异具有统计学意义(P<0.05)。簇状微钙化组14例(10例恶性)、散在微钙化组10例(5例恶性),2组比较具有统计学意义(P<0.05)。15例恶性患者同时病理确诊桥本氏甲状腺炎。结论非结节性甲状腺内微钙化患者甲状腺乳头状癌发生率较高,且与年龄,钙化集聚程度有关,年轻并具有桥本甲状腺炎患者,应特别重视。
Objective To study the clinical and ultrasound of non-nodular thyroid microcalcifications and their Association with Thyroid Cancer.Methods 24 patients with thyroid microcalcifications without definite nodules on US images were selected,Analysis of ultrasonographic features of patients,including the size and location of calcification area,according to the degree of calcification agglomeration.They were divided into 2 groups:focal distribution and diffuse distribution.Fine-needle aspiration biopsy(FNAB)was performed in all patients.According to the pathological results,the relationship between different age,sex,degree of calcification and thyroid carcinoma was analyzed.Results Among the 24 cases of non-nodular thyroid microcalcifications,there were 15 cases of PTC,with a malignant rate of 62.5%.The mean age of the malignant patients was 27.3 years,and that of benign patients was 39.1 years.There was significant difference between the 2 groups(P<0.05).There were significant differences between 14 cases(10 malignant cases)in the local distribution group and 10 cases(5 cases malignant)in the diffuse distribution group(P<0.05).15 malignant patients were pathologically diagnosed as Hashimoto’s thyroiditis.Conclusion The incidence of thyroid papillary carcinoma is higher in patients with microcalcifications in non-nodular thyroid,and it is related to age and the degree of calcification aggregation.Young patients with Hashimoto thyroiditis should be paid special attention to.
作者
谢雅娜
李兵
冀建峰
邱丽娜
肖秋金
XIE Ya'na;LI Bing;JI Jianfeng(The 908th Hospital of Chinese People's Liberation Army Joint Logistic Support Force,Nanchang,330002)
出处
《实用癌症杂志》
2023年第1期79-81,共3页
The Practical Journal of Cancer
关键词
甲状腺乳头状癌
甲状腺微钙化
超声
超声引导细针穿刺活检
Papillary thyroid cancer
Thyroid microcalcifications
Ultrasound
Ultrasound-guided fine-needle aspiration biopsy
