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间充质干细胞在2型糖尿病治疗中的应用

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摘要 干细胞的自我再生、分化潜能和免疫抑制性质已被证明显示在2型糖尿病的治疗效果。间充质干细胞避免了胚胎干细胞的伦理问题和诱导多能干细胞的致癌风险这些缺点,是目前2型糖尿病治疗中研究最多的细胞。2型糖尿病动物机制探索和间充质干细胞治疗研究都显示出间充质干细胞具备的修复胰岛β细胞、改善胰岛素抵抗、调节肝糖代谢、促进免疫抑制等作用可能转化为临床应用,但仍需更大的、随机的、双盲的和更好控制的实验以及更长的后续研究。
出处 《吉林医学》 CAS 2023年第1期187-193,共7页 Jilin Medical Journal
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