摘要
大脑中动脉夹层是引起青年缺血性卒中的少见病因,合并人类免疫缺陷病毒(HIV)感染的情况更为罕见。文中报道1例26岁HIV抗原/抗体阳性的急性脑梗患者,起病表现为内囊预警综合征,继而进展为右基底节区的脑梗死,磁共振高分辨率管壁成像扫描显示右侧大脑中动脉夹层“双腔征”和“内膜瓣征”的影像学表现。HIV感染常以HIV相关性血管病引起脑血管病,该例患者还合并血压变异系数增大的高血压病,二者均可增加大脑中动脉夹层的发生风险。结合文献报道,文中进一步探讨HIV感染与脑血管病之间的关系以及大脑中动脉夹层发生的可能机制。
Middle cerebral artery dissection is an uncommon cause of ischemic stroke in young adults,which is extremely rare in the case that it occurs in HIV-infected patients.This article reported a 26-year-old acute cerebral infarction patient with HIV antigen/antibody-positive who started with capsular warning syndrome and progressed to right basal ganglia cerebral infarction.The high-resolution vessel wall imaging showed the characteristic findings of middle cerebral artery dissection including"double luminal"and"intimal flap"signs.The coexistence of HIV-associated vasculopathy and hypertension with high blood pressure variability contributed to the occurrence of middle cerebral artery dissection in the patient.Combined with literature reports,this paper will further explore the relationship between HIV infection and cerebrovascular disease and the possible mechanism of middle cerebral artery dissection.
作者
侯晋
王建
郭玉坤
李恒
Hou Jin;Wang Jian;Guo Yukun;Li Heng(Department of Neurology,Central Hospital Affiliated to Shandong First Medical University,Jinan 250013,China;epartment of Radiology,Central Hospital Affiliated to Shandong First Medical University,Jinan 250013,China;Cheeloo College of Medicine,Shandong University,Jinan 250012,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2022年第12期1419-1422,共4页
Chinese Journal of Neurology
基金
国家自然科学基金(81701118)。
关键词
梗死
大脑中动脉
动脉夹层
HIV
Infarction,middle cerebral artery
Artery dissection
HIV