摘要
目的分析探讨基于六经辨证治疗新型冠状病毒肺炎疑似病例用药规律,为新型冠状病毒肺炎中医临床辨证论治提供临床思路。方法筛选2020年3月1日—2020年5月30日于广州中医药大学附属宝安中医院就诊并符合“新型冠状病毒肺炎疑似病例”标准,口服中药治疗,疗效显著,好转出院的病例107例,运用中医传承计算平台软件(V3.0),采用关联规则、基于k均值聚类算法与回归模型聚类分析等数据挖掘方法进行统计分析。结果共纳入处方118首,药物总计134味。六经分型中以太阳证、太阴证、少阳证频次较高。高频使用药物为甘草、乌梅、龙脷叶、麻黄、桂枝等;关联系数前3位为乌梅、麻黄、桂枝→甘草;甘草、龙脷叶、紫苏叶→乌梅;甘草、乌梅、桂枝→麻黄。对药物进行聚类分析,可将118首处方中的药物分为5类。结论本次研究的病例以太阳证、太阴证、少阳证为多,其中治疗太阳证以麻黄汤、葛根汤类方为主,治疗太阴证以茯苓杏仁甘草汤、苓甘五味姜辛汤类方为主,治疗少阳证以柴胡达原饮类方为主,从六经精准辨证,遣方用药,在临床上常能收到显著疗效。
Objective The analysis and discussion are based on the rule of medication for suspected cases of novel coronavirus pneumonia based on the differentiation of the six channels,and provide clinical ideas for the clinical diagnosis and treatment of new coronavirus pneumonia in traditional Chinese medicine.Methods Screening of 107 cases who were treated at Bao’an Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine from March 1 to May 30,2020 and met the criteria of"suspected cases of novel coronavirus pneumonia".Oral Chinese medicine treatment showed significant efficacy and improved and discharged 107 cases.Related information Data,establish a database,enter the"Traditional Chinese Medicine Inheritance Computing Platform Software(V3.0)",and use association rules,k-means clustering algorithm and regression model clustering analysis and other data mining methods for statistical analysis.Results A total of 118 prescriptions were included,with a total of 134 medicines.In the six meridian classification,the frequency of Sun syndrome,Taiyin syndrome and Shaoyang syndrome is higher.The high-frequency drugs used are:licorice,ebony,dragonfly leaf,ephedra,cassia twig,etc.the top three correlation coefficients are ebony plum,ephedra,cassia twig→licorice;licorice,dragonfly leaf,perilla leaves→ebony plum;licorice,ebony plum,Guizhi→Ephedra.Cluster analysis of drugs was performed,and the drugs in the 118 prescriptions were divided into 5 categories.Conclusion The cases in this study were mostly Sun Syndrome,Taiyin Syndrome,and Shaoyang Syndrome.Among them,Mahuang Decoction and Gegen Decoction were used to treat Sun Syndrome,and Fuling Almond Gancao Decoction and Linggan Wuwei Jiangxin Decoction were used to treat Taiyin Syndrome.Mainly,the treatment of Shaoyang syndrome is mainly based on Chaihuda Yuanyin prescriptions.According to the precise differentiation of the six meridians,the prescription of medicines can often receive significant clinical effects.
作者
费雨潇
吴凡伟
李佳凤
牛璇
卢晓鹏
FEI Yuxiao;WU Fanwei;LI Jiafeng;NIU Xuan;LU Xiaopeng(Bao’an Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,Shenzhen 518000,Guangdong,China)
出处
《实用中医内科杂志》
2022年第11期123-127,I0021,共6页
Journal of Practical Traditional Chinese Internal Medicine
基金
广东省中医药局科研项目(20182129)
深圳市科技创新基础研究项目(201884976)。
关键词
六经辨证
新型冠状病毒肺炎
疑似病例
数据挖掘
syndrome differentiation of six channels
COVID-19
suspected cases of novel coronavirus pneumonia
Data Mining
