摘要
目的分析重庆市南岸区细菌性痢疾临床诊断准确率、病原分布,为疾病防治提供基础数据。方法收集49例细菌性痢疾临床诊断患者的粪便样本,进行志贺菌、弯曲菌属、沙门菌、副溶血性弧菌、霍乱弧菌、致泻性大肠埃希菌、小肠结肠炎耶尔森菌、金黄色葡萄球菌8种致病菌的分离培养及血清分型。结果49例样本至少检出1种致病菌的概率为36.73%(18/49),其他致病菌检出率由高到低依次为弯曲菌属(22.45%,11/49)、致泻性大肠埃希菌(12.24%,6/49)、沙门菌属(6.12%,3/49)、金黄色葡萄球菌4.08%(2/49);未检出志贺菌、霍乱弧菌、副溶血性弧菌、小肠结肠炎耶尔森菌。结论重庆市南岸区细菌性痢疾流行情况低,临床诊断错误率较高。致病菌以弯曲菌属、致泻性大肠埃希菌、沙门菌属为优势构成,志贺菌属与其他肠道致病菌的快速鉴别诊断应尽快建立及推广应用。
Objective To analyze the clinical diagnostic accuracy rate and pathogen distribution of bacillary dysentery in Nan’an District,Chongqing City,so as to provide basic data for disease prevention and control.Methods A total of 49 clinical samples were collected from clinically diagnosed bacillary dysentery cases for the detections and serotyping of Shigella,Campylobacter,Salmonella,Vibrio parahaemolyticus,Vibrio cholerae,diarrheagenic Escherichia coli and Yersinia enterocolitica,Staphylococcus aureus.Results The positive rate of at least one pathogen in 49 samples was 36.73%(18/49),and the positive rate was 22.45%(11/49)for Campylobacter,12.24%(6/49)for diarrheic E.coli,6.12%(3/49)for Salmonella,and 4.08%for Staphylococcus aureus(2/49).Shigella,Vibrio cholerae,Vibrio parahaemolyticus and Yersinia enterocolitica were not detected.Conclusion The prevalence of bacillary dysentery is low and the error rate of clinical diagnosis is high in Nan’an District,Chongqing City.Campylobacter,diarrheic Escherichia coli and Salmonella are the dominant pathogenic bacteria.The rapid differential diagnosis of Shigella and other intestinal pathogenic bacteria should be established and popularized as soon as possible.
作者
宗华
孙巧
殷静
罗益
周思雨
李彩云
ZONG Hua;SUN Qiao;YIN Jing;LUO Yi;ZHOU Si-yu;LI Cai-yun(Nanan District Center for Diseases Control and Prevention,Chongqing 400000,China)
出处
《中国卫生检验杂志》
CAS
2022年第22期2702-2705,共4页
Chinese Journal of Health Laboratory Technology
基金
重庆市科卫联合医学科研项目(2020FYYX215)。
关键词
细菌性痢疾
临床诊断
志贺菌
弯曲菌
Bacillary dysentery
Clinical diagnosis
Shigella
Campylobacter
