摘要
目的:舍曲林联合家庭治疗对破坏性情绪失调障碍(DMDD)的临床疗效。方法:选取2019年1月—12月大庆市第三医院儿童青少年心理门诊收治的70例DMDD12~18岁患者作为研究对象,随机分为实验组和对照组,每组各35例,接受8周的治疗。结果:实验组与对照组在人口学资料及基线各量表评分上,差异无统计学意义(t=0.76、0.81、0.83、1.09、1.13,P>0.05)。治疗后,实验组汉密尔顿抑郁量表(HAMD)得分为(9.34±2.01)分、汉密顿焦虑量表(HAMA)得分为(8.67±1.29)分、临床疗效总评量表(CGI)得分为(2.65±0.28)分;对照组HAMD得分为(13.99±1.79)分、HAMA得分为(14.63±1.87)分、CGI得分为(3.03±0.37),实验组得分均显著低于对照组及基线水平,差异有统计学意义(t=0.65、1.32、0.98、2.54,P<0.05)。结论:舍曲林治疗DMDD有效,但舍曲林联合家庭治疗改善DMDD患者病情更明显。
Objective:To observe the clinical efficacy of sertraline combined with family therapy in the treatment of disruptive mood dysregulation disorder(DMDD).Methods:70 patients aged 12 to 18 years in the DMDD outpatient clinic of the hospital from January 2019 to December 2019 were selected and randomly divided into an experimental group and a control group, with 35patients in each group. All received 8 weeks of treatment.Results:There was no statistically significant difference between the experimental and control groups in demographic data and baseline scores on each scale(t=0.76, 0.81, 0.83, 1.09, 1.13, P>0.05). After treatment, the Hamilton depression scale(HAMD) score was(9.34±2.01), the Hamilton anxiety scale(HAMA) score was(8.67±1.29) points, and the total clinical outcome scale(CGI) score was(2.65±0.28) points in the experimental group. In the control group, the HAMD score was(13.99±1.79) points, the HAMA score was(14.63±1.87) points and the CGI score was(3.03±0.37)points. The scores of the experimental group were significantly lower than those of the control group and the baseline level, and the differences were statistically significant(t=0.65, 1.32, 0.98, 2.54, P<0.05).Conclusion:Sertraline is effective in the treatment of DMDD, but sertraline combined with home therapy improves the condition of patients with DMDD more significantly.
作者
任凯
栾悦
张丽威
王海娜
王婷婷
REN Kai;LUAN Yue;ZHANG Li-wei(Daqing Third Hospital,Daqing,Heilongjiang,163712,China)
出处
《黑龙江医学》
2022年第23期2828-2832,共5页
Heilongjiang Medical Journal
关键词
舍曲林
家庭治疗
破坏性情绪失调障碍
Sertraline
Family therapy
Disruptive mood dysregulation disorder
