摘要
目的探究对急性胆囊炎患者采用腹腔镜下三孔法胆囊切除术(LC),观察对患者的临床疗效、安全性。方法选择2020年7月—2021年12月本院收治的急性胆囊炎患者100例作为研究对象,分为对照组和研究组两组,每组各50例。研究组患者使用三孔法LC,对照组患者使用传统切除术,观察两组治疗前后炎症指标、免疫指标、肝功能指标、胃肠道,统计两组相关手术指标、术后并发症发生率。结果两组患者手术后TNF-α、IL-6、CRP、TBIL、GGT、AST高于手术前;CD4^(+)/CD8^(+)、CD3^(+)、IgA、IgM低于手术前(P<0.05)。研究组手术后TNF-α、IL-6、CRP、CD4^(+)/CD8^(+)、CD3^(+)、IgA、IgM低于手术前低于对照组;研究组手术后TBIL、GGT、AST高于对照组(P<0.05)。研究组胃肠道恢复时间、手术时间、术中出血量、住院时间均低于对照组(P<0.05)。对照组术后并发症发生率高于研究组(P<0.05)。结论对急性胆囊炎患者采用三孔法LC更好,可以降低炎症反应,减少患者的并发症发生率,临床疗效较好,安全性较高,值得在临床中推广。
Objective To explore the clinical efficacy and safety ofthree-port laparoscopic cholecystectomy(LC)for patients with acute cholecystitis.Methods The 100 patients with acute cholecystitisadmitted to our hospital from July 2020 to December 2021were selected as stud subjects.They were randomly divided intoa control group anda study group,with 50 patients in each group.Patients in the study group adoptedthree-port laparoscopic cholecystectomy,and patients in the control group received traditional resection.The inflammation index,immunity index,liver function index,and gastrointestinal tract were observed before and after treatment in the two groups.The operative indexes and the incidence of postoperative complications in the two groups were calculated.Results The concentration of TNF-α,IL-6,CRP,TBIL,GGT,and AST of the two groups after the operation were higher than before surgery.However,the levels of CD4^(+)/CD8^(+),CD3^(+),IgA,and IgM were lower than those before surgery(P<0.05).After operation,the levels of TNF-α,IL-6,CRP,CD4^(+)/CD8^(+),CD3^(+),IgA,and IgM in the study group were lower than those in the control group;levels of TBIL,GGT,and AST were higher than those in the control group(P<0.05).The gastrointestinal recovery time,operation time,intraoperative bleeding amount,and hospital stay in the study group were lower than those in the control group(P<0.05).The postoperative complication rate was higher in the control group than in the study group(P<0.05).Conclusions The three-port laparoscopic cholecystectomyfor patients with acute cholecystitis is better than traditional surgery.It could reduce the inflammatory response and reduce the incidence of complications in patients,with good clinical efficacy and high safety,and is worth popularizing in clinical practice.
作者
曹磊
陈守华
吕约晟
Cao Lei;Chen Shouhua;Lv Yuesheng(The fourth people's hospital of Shangqiu city,Shangqiu,Henan,476000,China)
出处
《齐齐哈尔医学院学报》
2022年第19期1841-1844,共4页
Journal of Qiqihar Medical University
