摘要
目的:分析急性心肌梗死(AMI)患者血浆B型脑钠肽(BNP)、C反应蛋白(CRP)及血沉(ESR)变化与病情及预后的关系。方法:选取130例AMI患者作为研究对象,按照是否出现心血管事件分为预后不良组(n=42)与预后良好组(n=88),并取同期130名健康体检者纳入对照组。比较各组一般资料、入院时ESR、血浆BNP和CRP水平;比较不同病变程度患者入院时ESR、血浆BNP和CRP水平,并分析其与病变程度相关性。结果:预后不良组病变支数大于预后良好组(P<0.05);各组ESR、血浆BNP和CRP水平比较:预后不良组>预后良好组>对照组,差异有统计学意义(P<0.05);不同病变程度ESR、血浆BNP和CRP水平比较:3支>2支>单支,差异有统计学意义(P<0.05);ESR、血浆BNP和CRP水平与病变程度正相关(P<0.05)。结论:ES R、血浆BNP和CRP水平与AMI患者病情及预后具有紧密联系,可用于预测其病情与预后情况。
Objective:To analyze the relationship between levels of erythrocyte sedimentation rate(ESR),brain natriuretic peptide(BNP),C-reactive protein(CRP)and illness state,prognosis of patients with acute myocardial infarction(AMI).Methods:130 patients with AMI were selected as the study subjects.They were divided into poor prognosis group(n=42)and good prognosis group(n=88)according to the presence or absence of cardiovascular events.130 healthy subjects in the same period were included as the control group.The general data,levels of ESR,BNP and CRP at admission were compared among the three groups.The levels of ESR,BNP and CRP of patients with different lesion degrees were compared at admission,and their correlation with lesion degrees was analyzed.Results:The number of lesions in the poor prognosis group was significantly more than that in the good prognosis group(P<0.05).Arranging the levels of ESR,BNP and CRP from high to low,the corresponding order was poor prognosis group,good prognosis group and the control group(P<0.05).Arranging the above indexes from high to low,the corresponding order was 3 lesions,2 lesions and single lesion(P<0.05).The levels of ESR,BNP and CRP were positively correlated with the lesion degrees(P<0.05).Conclusion:The levels of ESR,BNP and CRP are closely related to the illness state and prognosis of patients with AMI,which can be used to predict their illness state and prognosis.
作者
江希
汪汉
王春斌
JIANG Xi;WANG Han;WANG Chun-bin(Department of Cardiology,the Third People's Hospital of Chengdu,Chengdu 610031,Sichuan,China)
出处
《川北医学院学报》
CAS
2022年第12期1563-1565,共3页
Journal of North Sichuan Medical College
基金
四川省卫生和计划生育委员会科研课题(16PJ042)。
关键词
急性心肌梗死
血沉
B型脑钠肽
C反应蛋白
病情
预后
Acute myocardial infarction
Erythrocyte sedimentation rate
Brain natriuretic peptide B
C-reactive protein
Illness state
Prognosis
