摘要
目的:探究37~40℃冲洗液对腹部手术患者血流动力学、应激指标及凝血功能的影响。方法:选取103例行腹部手术患者作为研究对象,按照随机数字表法分为常规组和加温组。常规组51例给予保温毯+室温冲洗液处理,加温组52例给予保温毯+37~40℃冲洗液处理。分析两组血流动力学、应激指标和凝血功能。结果:两组手术结束后的心率(HR)、平均动脉压(MAP)、心肌耗氧量高于干预前,加温组低于常规组,差异有统计学意义(P<0.05);C反应蛋白(CRP)、肾上腺激素(AD)、去甲肾上腺激素(NE)水平高于干预前,加温组低于常规组(P<0.05);两组手术结束后的活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)延长,加温组短于常规组;纤维蛋白原(FIB)水平高于干预前,加温组低于常规组(P<0.05)。结论:37~40℃冲洗液干预腹部手术患者,可调节应激反应,改善血流动力学和凝血功能。
Objective: To investigate the effect of 37-40 ℃ rinse solution on the hemodynamic level, stress index and coagulation function of patients undergoing abdominal surgery. Methods: A total of 103 patients undergoing abdominal surgery were selected as the research objects and randomized into the conventional group and heating group. 51 patients in the conventional group were given thermal insulation blanket together with room temperature rinse solution, while another 52 patients in the heating group were treated with thermal insulation blanket plus rinse solution warmed to 37-40 ℃. Then, the hemodynamics, stress indexes and coagulation function of patients were compared between the two groups. Results: The levels of heart rate(HR), mean arterial pressure(MAP) and myocardial oxygen consumption in both groups were increased at the end of operation compared with those before intervention, but HR, MAP and myocardial oxygen consumption levels in heating group were lower than those in conventional group, and the differences were statistically significant(P< 0.05);the levels of C-reactive protein(CRP), adrenal hormone(AD) and norepinephrine hormone(NE) in both groups were increased after operation compared with those before intervention, and the increase range in heating group was lower than that in conventional group(P<0.05);after surgery, the activated partial thrombin time(APTT), prothrombin time(PT), thrombin time(TT) and fibrinogen(FIB) in both groups were prolonged compared with those before intervention, and the prolonged degree in the heating group was less than that in conventional group(P< 0.05). Conclusion: For patients undergoing abdominal surgery, the intervention of 37-40 ℃ rinse solution can regulate their stress responses, improve their hemodynamics and coagulation functions.
作者
王品
唐智华
王文文
WANG Pin;TANG Zhihua;WANG Wenwen(Operating Room,the 1st Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China;Gynecology,the 1st Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《华夏医学》
CAS
2022年第5期124-127,共4页
Acta Medicinae Sinica
关键词
冲洗液
腹部手术
血流动力学
应激指标
rinse solution
abdominal surgery
hemodynamics
stress index
