摘要
声动力疗法(sonodynamic therapy,SDT)是一种新兴的癌症治疗方法,具有精确度高、组织穿透力优良、患者依从性高、不良反应少等优点,临床应用前景广阔。该文介绍了声动力疗法的机制及声敏剂的种类,阐述了增强声动力疗法的策略,并总结了声动力联合疗法的研究进展。
Sonodynamic therapy(SDT)is a newly developed therapeutic approach.Due to its high accuracy,deep tissue penetration,high compliance in patients,and rare adverse effects,it has great potential in clinical application.This paper briefly introduced the mechanisms of SDT and different types of sonosensitizers,elaborated various strategies for enhanced SDT,and summarized the advances in the combination of SDT with other therapies.
作者
刘允
LIU Yun(School of Pharmacy,Guangdong Medical University,Dongguan 523808,China)
出处
《广东医科大学学报》
2022年第6期603-612,共10页
Journal of Guangdong Medical University
基金
国家自然科学基金青年项目(51903060)
广东省基础与应用基础研究基金自然科学基金面上项目(2020A1515011244)
广东医科大学高层次人才启动经费(4SG18001Gb)。
关键词
声动力疗法
肿瘤
纳米载体
肿瘤微环境
sonodynamic therapy
tumor
nanocarriers
tumor microenvironment
