摘要
地下水中全氟辛酸(perfluorooctanoic acid,PFOA)和全氟辛基磺酸(perfluorooctanesulfonic acid,PFOS)检测具有重要的环境污染物控制意义,目前主要依赖固相萃取-液质联用内标法技术。文中开发了一种适用于地下水直接进样,乙酸铵-水溶液和乙腈溶液梯度洗脱,高效液相色谱-串联质谱法(HPLC-MS/MS)的多反应监测(MRM)模式的外标检测方法。标准溶液在0.05~1μg·L^(-1)范围内,浓度与响应值有良好的线性关系,相关系数超过0.99,方法的检出限达到PFOA:0.01μg·L^(-1),PFOS:0.01μg·L^(-1);回收率为PFOA:101%~103%、PFOS:94.0%~96.5%;相对标准偏差(RSD)为PFOA:1.4%~3.5%(n=6),PFOS:1.3%~9.6%(n=6)。结果表明,该方法前处理简便,灵敏度高、重现性好、准确度高,分析速度快,适用于地下水中PFOA和PFOS的大批量定性、定量检测。
The detection of PFOA(perfluorooctanoic acid)and PFOS(perfluorooctanesulfonic acid)in groundwater is of great significance for the control of environmental pollutants.Currently,solid-phase extraction-HPLC-MS/MS with internal standards method is mainly used.In this paper,a method of direct injection of groundwater,gradient elution of ammonium acetate-water solution and acetonitrile solution,and high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)with external standards was developed.The linear range of substances was 0.05~1μg·L^(-1)with the correlation coefficient(r)greater than 0.99.The method detection limit of the method was 0.01μg·L^(-1)for PFOA and 0.01μg·L^(-1)for PFOS.The spiked recovery rate was 101%~103%for PFOA and 94.0%~96.5%for PFOS.The relative standard deviation(n=6)was 1.4%~3.5%for PFOA and 1.3%~9.6%for PFOS.The results showed that the method had simple treatment,high sensitivity,good reproducibility,high accuracy and fast analysis speed,and was suitable for mass qualitative and quantitative detection of PFOA and PFOS in groundwater.
作者
朱晓玲
赵颖
白立雯
ZHU Xiao-ling;ZHAO Ying;BAI Li-wen(SUEZ Environmental Testing Technology(Shanghai)Co.,Ltd.,Shanghai 201206,China)
出处
《化学研究与应用》
CAS
CSCD
北大核心
2022年第12期3004-3008,共5页
Chemical Research and Application
关键词
PFOA
PFOS
超高效液相色谱
串联质谱
地下水
PFOA
PFOS
ultra-high performance liquid chromatography
tandem mass spectrometry
groundwater
