摘要
目的 对比宫颈癌筛查中阴道镜下宫颈活组织病理检测与宫颈锥切病理诊断的有效性。方法 选取60例接受宫颈癌筛查的住院患者为研究对象。所有患者均开展阴道镜下宫颈活组织病理检测与宫颈锥切病理诊断,将宫颈锥切病理诊断结果作为参照标准,分析阴道镜下宫颈活组织病理检测的诊断效果。结果 阴道镜下宫颈活组织病理检测疾病诊断准确率(81.67%)与宫颈锥切病理诊断率(100%)相比,差异有统计学意义(P<0.05);其中CIN1级、CIN2级与3级及原位癌检出率为18.33%、50.00%与宫颈锥切病理诊断的21.67%、56.67%对比,差异无统计学意义(P>0.05),但微小浸润癌检出率(13.33%)低于宫颈锥切病理诊断率(21.67%),差异有统计学意义(P<0.05);阴道镜下宫颈活组织病理检测的疾病诊断特异性76.92%与宫颈锥切病理诊断的100%比较差异无统计学意义(P>0.05),但敏感性82.98%低于宫颈锥切病理诊断的100%,差异有统计学意义(P<0.05)。结论 宫颈癌筛查异常中应用阴道镜下宫颈活组织病理检测在微小浸润癌方面漏诊风险较高,若以此方式诊断为CIN高级别者应联合开展宫颈锥切病理诊断,以确保诊断结果的准确率。
Objective To compare the effectiveness of colposcopy cervical biopsy and cervical conization pathological diagnosis in cervical cancer screening. Methods 60 inpatients receiving cervical cancer screening were selected as subjects. All patients underwent colposcopy cervical biopsy and cervical conectomy pathological diagnosis. The results of cervical conectomy pathological diagnosis were used as reference standards to analyze the diagnostic effect of colposcopy cervical biopsy. Results The diagnostic accuracy of cervical biopsy under colposcopy(81.67%) was significantly higher than that of cervical conectomy(100%)(P<0.05). Among them, the detection rates of CIN1, CIN2 and CIN3 and in situ cancer were 18.33% and 50.00%, respectively,compared with 21.67% and 56.67% in the pathological diagnosis of cervical conical resection(P>0.05), but the detection rate of small invasive cancer(13.33%) was lower than that of the pathological diagnosis of cervical conical resection(21.67%). The difference was statistically significant(P<0.05). The diagnostic specificity of cervical biopsy under colposcopy was 76.92% compared with that of cervical conical biopsy(100%), but the sensitivity of 82.98% was lower than that of cervical conical biopsy(100%), the difference was statistically significant(P<0.05). Conclusion The application of colposcopy cervical biopsy in abnormal cervical cancer screening has a higher risk of missed diagnosis of micro-invasive cancer. Therefore, if the patient is diagnosed with high-grade CIN in this way, cervical conization should be combined with pathological diagnosis to ensure that The accuracy of diagnostic results.
作者
耿歆
沈亚杰
Geng Xin;Shen Yajie(Department of Pathology,The First People's Hospital of Zhenjiang,Zhenjiang 212000,China;Department of Gynecology,The First People's Hospital of Zhenjiang,Zhenjiang 212000,China)
出处
《实用妇科内分泌电子杂志》
2021年第32期62-64,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
宫颈癌
筛查
阴道镜
宫颈活组织病理检测
宫颈锥切
病理诊断
Cervical cancer
Screening
Colposcope
Cervical biopsy pathology
Cervical conical incision
Pathological diagnosis
