摘要
目的探讨支气管镜手术中应用舒芬太尼联合丙泊酚麻醉对患者呼吸及认知功能的影响。方法98例肺炎患者,采用随机数字表法分为A组与B组,各49例。两组均行支气管镜手术,A组采用舒芬太尼联合丙泊酚麻醉,B组采用舒芬太尼联合地佐辛麻醉。比较两组围术期呼吸参数、麻醉苏醒后认知功能评分、不良反应发生情况。结果诱导后3 min、手术开始3 min、苏醒时,A组的呼吸频率(RR)、吸气峰流速(PIFR)分别为(17.87±0.31)次/min、(0.30±0.01)L/s,(18.91±0.41)次/min、(0.28±0.01)L/s,(18.99±0.35)次/min、(0.38±0.01)L/s,快于B组的(15.86±0.32)次/min、(0.24±0.01)L/s,(15.82±0.40)次/min、(0.21±0.01)L/s,(18.11±0.31)次/min、(0.31±0.01)L/s;潮气量(VT)、分钟通气量(MV)分别为(3.31±0.16)L、(5.91±0.15)L/min,(3.70±0.19)L、(6.83±0.27)L/min,(4.39±0.13)L、(9.05±0.32)L/min,高于B组的(2.71±0.09)L、(4.10±0.21)L/min,(2.74±0.17)L、(4.40±0.19)L/min,(3.80±0.12)L、(6.90±0.30)L/min,差异均有统计学意义(P<0.05)。A组麻醉苏醒后的语言能力、记忆能力、定向力、意识与注意力、结构能力、计算能力、推理能力评分分别为(24.01±1.47)、(8.95±1.47)、(11.73±1.08)、(8.10±0.90)、(4.80±0.77)、(3.80±0.31)、(10.75±1.23)分,均高于B组的(18.84±1.31)、(7.30±1.31)、(9.91±0.85)、(6.26±2.76)、(3.98±0.87)、(3.06±0.27)、(8.44±0.82)分,差异有统计学意义(P<0.05)。A组不良反应发生率为4.1%,低于B组的16.3%,差异有统计学意义(P<0.05)。结论支气管镜手术中应用舒芬太尼注射液联合丙泊酚注射液的麻醉效果良好,对呼吸功能、认知功能影响小。
Objective To discuss the effect of sufentanil combined with propofol anesthesia on respiratory and cognitive function in patients with bronchoscopic surgery.Methods A total of 98 patients with pneumonia were divided into group A and group B by random numerical table,with 49 cases in each group.Both groups underwent bronchoscopic surgery.Group A was anesthetized with sufentanil and propofol,and group B was anesthetized with sufentanil and dezocine.The perioperative respiratory parameters,cognitive function scores after recovery from anesthesia,and occurrence of adverse reactions were compared between the two groups.Results At 3 min after induction,3 min after surgery,and when waking up,the respiratory rate(RR)and peak inspiratory flow rate(PIFR)of group A were(17.87±0.31)times/min and(0.30±0.01)L/s,(18.91±0.41)times/min and(0.28±0.01)L/s,(18.99±0.35)times/min and(0.38±0.01)L/s,which were faster than(15.86±0.32)times/min and(0.24±0.01)L/s,(15.82±0.40)times/min and(0.21±0.01)L/s,(18.11±0.31)times/min and(0.31±0.01)L/s of group B;the tidal volume(VT)and minute ventilation(MV)of group A were(3.31±0.16)L and(5.91±0.15)L/min,(3.70±0.19)L and(6.83±0.27)L/min,(4.39±0.13)L and(9.05±0.32)L/min,which were higher than(2.71±0.09)L and(4.10±0.21)L/min,(2.74±0.17)L and(4.40±0.19)L/min,(3.80±0.12)L and(6.90±0.30)L/min of group B;the differences were all statistically significant(P<0.05).The scores of verbal ability,memory,orientation,awareness and attention,structural ability,computational ability,and reasoning ability in group A after recovery from anesthesia were(24.01±1.47),(8.95±1.47),(11.73±1.08),(8.10±0.90),(4.80±0.77),(3.80±0.31),and(10.75±1.23)points,which were higher than(18.84±1.31),(7.30±1.31),(9.91±0.85),(6.26±2.76),(3.98±0.87),(3.06±0.27),and(8.44±0.82)points of group B,and the differences were all statistically significant(P<0.05).The incidence of adverse reactions in group A was 4.1%,which was lower than 16.3%in group B,and the difference was statistically significant(P<0.05).C
作者
黄丽军
张斯民
连志坚
HUANG Li-jun;ZHANG Si-min;LIAN Zhi-jian(Department of Nursing,Dehua County Hospital Affiliated to Huaqiao University,Fuzhou 361025,China)
出处
《中国现代药物应用》
2022年第21期77-80,共4页
Chinese Journal of Modern Drug Application
关键词
支气管镜
舒芬太尼
丙泊酚
地佐辛
呼吸功能
认知功能
Bronchoscope
Sufentanil
Propofol
Dezocine
Respiratory function
cognitive function
