摘要
目的研究一次性根管治疗牙体牙髓病的效果及对患者咀嚼功能和炎性因子的影响。方法160例牙体牙髓病患者,按随机数字表法分为对照组与实验组,每组80例。实验组予以一次性根管治疗,对照组予以重复多次根管法治疗。对比两组治疗效果及治疗前后咀嚼功能(牙咬合力、咀嚼效率、牙龈指数)、炎性因子(白细胞介素-6、C反应蛋白、肿瘤坏死因子-α)水平。结果实验组患者治疗总有效率为97.50%,显著高于对照组的82.50%,差异具有统计学意义(P<0.05)。治疗后,两组患者牙咬合力、咀嚼效率较治疗前升高,牙龈指数较治疗前降低,且实验组患者牙咬合力(130.86±9.71)Ibs、咀嚼效率(86.31±5.37)%高于对照组的(113.64±5.62)Ibs、(72.56±4.86)%,牙龈指数(0.36±0.11)低于对照组的(0.61±0.12),差异均有统计学意义(P<0.05)。治疗后,两组患者白细胞介素-6、C反应蛋白、肿瘤坏死因子-α水平均低于治疗前,且实验组患者白细胞介素-6(1.01±0.79)ng/L、C反应蛋白(4.05±1.37)mg/L、肿瘤坏死因子-α(3.02±0.46)ng/L均低于对照组的(1.77±0.42)ng/L、(7.45±1.33)mg/L、(6.03±0.87)ng/L,差异具有统计学意义(P<0.05)。结论一次性根管治疗牙体牙髓病患者的疗效显著,有助于患者咀嚼功能的恢复,并降低炎性因子水平。
Objective To study the effect of disposable root canal therapy in patients with dental pulp disease and its influence on masticatory function and inflammatory factors.Methods A total of 160 patients with dental pulp disease were divided into the control group and the experimental group according to the random numerical table,with 80 cases in each group.The experimental group received disposable root canal therapy,while the control group received repeated root canal therapy.Both groups were compared in terms of therapeutic effect,masticatory function(occlusal force,masticatory efficiency,gingival index),and levels of inflammatory factors(interleukin-6,C-reactive protein,tumor necrosis factor-α)before and after treatment.Results The total effective rate in the experimental group was 97.50%,which was significantly higher than 82.50%in the control group,and the difference was statistically significant(P<0.05).After treatment,the occlusal force and masticatory efficiency of the two groups were higher than those of this group before treatment,and the gingival index was lower than that of this group before treatment;the occlusal force(130.86±9.71)Ibs and masticatory efficiency(86.31±5.37)%of the experimental group were higher than(113.64±5.62)Ibs and(72.56±4.86)%of the control group;the gingival index(0.36±0.11)of the experimental group was lower than(0.61±0.12)of the control group group;the differences were all statistically significant(P<0.05).After treatment,the levels of interleukin-6,C-reactive protein and tumor necrosis factor-αin both groups were lower than those before treatment in this group;the interleukin-6(1.01±0.79)ng/L,C-reactive protein(4.05±1.37)mg/L,and tumor necrosis factor-α(3.02±0.46)ng/L in the experimental group were lower than(1.77±0.42)ng/L,(7.45±1.33)mg/L,and(6.03±0.87)ng/L in the control group;the differences were all statistically significant(P<0.05).Conclusion Disposable root canal therapy has significant efficacy on patients with dental pulp disease,and can help restore the ma
作者
杜小沛
张婷婷
韩宇
邱伟
杜启涛
DU Xiao-pei;ZHANG Ting-ting;HAN Yu(Department of Cariology and Endodontics,Dalian Stomatological Hospital,Dalian 116021,China)
出处
《中国现代药物应用》
2022年第21期45-48,共4页
Chinese Journal of Modern Drug Application
关键词
一次性根管
牙体牙髓病
咀嚼功能
炎性因子
Disposable root canal therapy
Dental pulp disease
Masticatory function
Inflammatory factors
