摘要
目的探讨彩色多普勒超声联合肌酸激酶(CK)对凶险型前置胎盘合并胎盘植入的预测价值分析。方法收集2019年1月至2021年11月我院收治的102例凶险型前置胎盘患者的一般资料、临床以及随访资料进行回顾性分析,根据出院诊断分为植入组(47例)和非植入组(55例),另外再随机抽取同期分娩的既往有剖宫产史,本次为正常妊娠的孕妇50例作为对照组。入院24 h内检测3组患者CK水平,并行彩色多普勒超声检查,对检测结果进行统计分析。绘制受试者工作特征(ROC)曲线,比较和观察彩色多普勒超声联合CK、彩色多普勒超声、CK诊断凶险型前置胎盘合并胎盘植入的预测价值。结果(1)3组孕妇血清CK水平比较差异有统计学意义(P<0.05),植入组血清CK水平明显高于非植入组和对照组(P<0.05);非植入组血清CK水平与对照组比较差异无统计学意义(P>0.05)。(2)中央型前置胎盘术后诊断凶险型前置胎盘合并胎盘植入的比例明显高于部分型前置胎盘和边缘型前置胎盘,差异有统计学意义(χ^(2)=4.97,P=0.008)。(3)ROC曲线结果显示彩色多普勒超声、CK在ROC曲线下的面积均>0.8;彩色多普勒联合CK后对凶险型前置胎盘合并胎盘植入的预测价值,灵敏度为78.11%,特异度为100%。结论CK可作为凶险型前置胎盘合并胎盘植入的特异性指标,且联合彩色多普勒超声诊断凶险型前置胎盘合并胎盘植入具有临床价值。
Objective To investigate the predictive value of color Doppler ultrasound combined with creatine kinase(CK)on dangerous placenta previa combined with placenta implantation.Methods The general data,clinical and follow-up data of 102 patients with dangerous placenta previa with placenta implantation admitted to our hospital from January 2019 to November 2021 were retrospectively analyzed.According to the discharge diagno-sis,they were divided into the implantation group(47 cases)and the non-implantation group(55 cases).In addition,the previous cesarean section history was randomly selected.Fifty normal pregnant women were selected as the control group.The CK levels of the three groups were detected within 24 hours after admission,and the results were statistically analyzed by color Doppler ultrasound.The receiver operator characteristic(ROC)curve was drawn to compare and observe the predictive value of color Doppler ultrasound combined with CK,color Doppler ultrasound and CK in the diagnosis of dangerous placenta previa with placenta implantation.Results There were significant differences in serum CK levels among the three groups(P<0.05).The serum CK levels in the implantation group were significantly higher than those in the non-implantation group and the control group(P<0.05).There was no significant difference in serum CK level between the non-implanted group and the control group(P>0.05).The proportion of dangerous placenta previa combined with placenta accreta after central placenta previa surgery was signif-icantly higher than that of partial placenta previa and marginal placenta previa(χ^(2)=4.97,P=0.008).According to the ROC curve results,the area under the ROC curve of color Doppler ultrasound and CK was more than 0.8.The sensitivity and specificity of color Doppler combined with CK for the prediction of dangerous placenta previa with placenta implantation were 78.11%and 100%,respectively.Conclusion CK can be used as a specific index of dangerous placenta previa combined with placenta implantation.
作者
毕卓芳
杨弋
陈国新
Bi Zhuofang;Yang Yi;Chen Guoxin(Department of Uttrasound,Sihui People's Hospital,Guangdong 526200,China;不详)
出处
《山西医药杂志》
CAS
2022年第18期2052-2054,共3页
Shanxi Medical Journal
基金
广东省肇庆市科技计划(201904031467)。
关键词
超声检查
多普勒
彩色
肌酸激酶
前置胎盘
预测
胎盘植入
Ultrasonography
Doppler
color
Creatine kinase
Placenta previa
Forecasting
Placenta implantation
