摘要
目的探讨动态血压监测对心力衰竭住院患者预后评估价值。方法选取2015年9月至2016年9月于金山区亭林医院就诊的心力衰竭患者206例为研究对象,入院常规行动态血压监测,并随访3年收集累积心力衰竭相关死亡事件,比较不同的动态血压组间死亡事件的发生率,并采用单因素和多因素Cox回归模型分析死亡风险与动态血压的关系。结果共有206例心力衰竭患者纳入分析,根据24 h平均收缩压(24 h SBP)将患者分为两组:24 h SBP<120 mm Hg组55例,24 h SBP≥120 mm Hg组151例。24 h SBP<120 mm Hg组3年累积心力衰竭相关病死率为10.91%,24 h SBP≥120 mm Hg组3年累积心力衰竭相关病死率为1.32%,两组比较差异有统计学意义(P<0.05)。单因素和多因素COX回归分析结果显示,24 h SBP<120 mm Hg组患者的3年累积心力衰竭相关死亡风险分别是24 h SBP≥120 mm Hg组患者的6.410倍(95%CI 1.701~25.316,P<0.05)和4.593倍(95%CI 1.210~17.429,P<0.05)。结论24 h SBP<120 mm Hg的心力衰竭患者与预后不良有关。
Objective To investigate the value of ambulatory blood pressure monitoring in assessing the prognosis of patients hospitalized with heart failure.Methods A total of 206 patients with heart failure who attended Tinglin Hospital in Jinshan District from September 2015 to September 2016 were selected for the study.Ambulatory blood pressure monitoring was routinely performed on admission,and cumulative heart failure-related deaths were collected at 3 years of follow-up,the incidence of death events between different ambulatory blood pressure groups were compared.Univariate and multifactorial Cox regression model was used to analyze the relationship between risk of death and ambulatory blood pressure.Results A total of 206 patients with heart failure were included in the analysis,and the patients were divided into two groups according to the 24 h mean systolic blood pressure(24 h SBP):55 patients in the 24 h SBP<120 mm Hg group and 151 patients in the 24 h SBP≥120 mm Hg group.The 3-year cumulative heart failure-related morbidity and mortality rate was 10.91%in the 24 h SBP<120 mm Hg group and 1.32%in the 24 h SBP≥120 mm Hg group,the difference between the two groups was statistically significant(P<0.05).Univariate and multifactorial COX regression analysis showed that the 3-year cumulative risk of heart failure-related death was 6.410 times(95%CI 1.701-25.316,P<0.05)and 4.593 times(95%CI 1.210-17.429,P<0.05).Conclusion Heart failure patients with 24 h SBP<120 mm Hg associates with adverse outcomes in the post-discharged prognosis.
作者
周勤
姚义安
吴春锋
张妙连
邵春蕾
张艳萍
ZHOU Qin;YAO Yi′an;WU Chunfeng;ZHANG Miaolian;SHAO Chunlei;ZHANG Yanping(Department of Cardiovascular Medicine,Tinglin Hospital,Shanghai 201505,China;Department of Cardiovascular Medicine,Tongji Hospital Affiliated to Shanghai Tongji University,Shanghai 200065,China)
出处
《检验医学与临床》
CAS
2022年第24期3364-3367,3372,共5页
Laboratory Medicine and Clinic
基金
上海市金山区科委课题(2015-3-29)
关键词
心力衰竭
24
h平均收缩压
动态血压监测
heart failure
24 h mean systolic blood pressure
ambulatory blood pressure monitoring
