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中医学习时间对医学命题认知影响的事件相关电位研究

Effect of Years of Study in Traditional Chinese Medicine on Cognition of Medical Propositions:An Event Related Potential Study
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摘要 目的:应用事件相关电位技术探索中医学习时间不同的医学生对医学命题加工的差异。方法:采用尾词范式与句义正确性判断任务,分别以中医相关专业研究生和大二生作为研究对象,提取并分析被试者在理解判断中医、西医命题时产生的行为学和脑电数据。应用重复测量方差分析对早期左前负成分(ELAN)、200 ms事件相关电位正波(P200)、400 ms事件相关电位负波(N400)、晚期正成分(LPC)时间窗的结果数据进行统计。结果:在N400时间窗,大二生比研究生诱发了更负的波幅,组别主效应呈边缘显著[F_((1,27))=4.01,P=0.06,η^(2)=0.13];在LPC时间窗,组别与命题类型的交互作用显著[F_((2,54))=3.57,P=0.04,η^(2)=0.12],大二生内,中医命题比西医命题诱发了更大的晚期正成分(P=0.01)。研究生内,中西医命题间未发现显著差异(P=0.27)。结论:拥有不同中医学习时间的学生对中西医命题的理解过程存在差异,随着知识水平的增高,中医学生可能不再关注中医学本身的隐喻特质,倾向于将中医抽象概念进行西医命题的具体化加工,促使中西医概念的理解呈现更多相通之处。 Objective:To explore the differences in medical proposition processing among medical students with different years of study in traditional Chinese medicine(TCM)using event related potential(ERP)technique.Methods:With TCM postgraduates and sophomores as research subjects,suffix paradigm and sentence correctness judgment task were performed to extract and analyze the behavioral and EEG data of the subjects in understanding and judging TCM and western medicine propositions.Repeated measures ANOVA was used to analyze the early left anterior negativity(ELAN),P200,N400 and late positive component(LPC)time windows.Results:In N400 time window,the sophomore group induced more negative amplitudes than the postgraduate group,and the main effect of group was marginally significant[F_((1,27))=4.01,P=0.06,η^(2)=0.13].In LPC time window,the interaction between groups and proposition types was distinct[F_((2,54))=3.57,P=0.04,η^(2)=0.12],and in the sophomore group,TCM propositions elicited a larger LPC amplitude than western medicine propositions(P=0.01).In the postgraduate group,no significant difference was found between TCM and western medicine prepositions(P=0.27).Conclusion:Students with different years of study in TCM have different understanding processes of TCM and Western medicine propositions.With the increase of knowledge level,TCM students may no longer pay attention to the metaphorical characteristics of TCM itself,and tend to concretely process the abstract TCM concepts into western medicine propositions,showing more similarities in understanding TCM and western medicine concepts.
作者 窦嘉乐 黄慧雯 吴彤 刘庆华 贾春华 刘丹彤 李鹏英 DOU Jiale;HUANG Huiwen;WU Tong;LIU Qinghua;JIA Chunhua;LIU Dantong;LI Pengying(School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;School of Basic Medicine,Zhejiang Chinese Medical University,Hangzhou 310053,China;School of Basic Medical Sciences,Shaanxi University of Chinese Medicine,Xianyang 712046,China)
出处 《世界中医药》 CAS 2022年第23期3313-3317,3324,共6页 World Chinese Medicine
基金 国家自然科学基金项目(81874514)——基于事件相关电位与功能性磁共振成像技术的中医语言研究 国家自然科学基金项目(82074582)——中医五行推理的逻辑解析与ERP及fMRI的实证研究。
关键词 中医理论 西医理论 医学命题 知识水平 思维差异 隐喻认知 事件相关电位 400 ms事件相关电位负波 晚期正成分 Traditional Chinese medicine theory Western medicine theory Medical proposition Knowledge level Thinking difference Metaphorical cognition Event related potential N400 Late positive component
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