摘要
Fibonacci number spiral patterns can be found in nature,particularly in plants,such as the sunflowers and phyllotaxis.Here,we demonstrated this pattern can be reproduced spontaneously within self-assembling peptide nanofibril films.By high-temperature water vapor annealing of an amorphous film containing both peptide and cationic diamines,well-defined amyloid-like nanofibrils can be assembled spontaneously,during which the nanofibrils will hierarchically stack with each other following the Fibonacci number patterns.The formation of the patterns is a selftemplated process,which involves stepwise chiral amplification from the molecular scale to the nano-and micro-scales.Moreover,by controlling the diameter,length,and handedness of the nanofibrils,various complex hierarchical structures could be formed,including vertically aligned nanoarray,mesoscale helical bundles,Fibonacci number spirals,and then helical toroids.The results provide new insights into the chiral self-assembly of simple biological molecules,which can advance their applications in optics and templated synthesis.
斐波那契螺旋普遍存在于自然界中,尤其是在植物如向日葵和叶序中.我们证明这种螺旋结构能够在自组装二肽薄膜内自发形成.通过对含有二肽和阳离子二胺的无定型薄膜进行高温水蒸气退火,二肽会自发地组装形成具有特定结构的淀粉样纳米纤维,这些纳米纤维将进一步按照斐波那契螺旋进行多级组装.该螺旋图案的形成是一个自模板的过程,涉及从分子尺度到纳米和微米尺度的逐级手性放大.此外,通过控制纳米纤维的直径、长度和手性,可以形成多种复杂的螺旋结构,包括垂直站立的纳米阵列、螺旋束、斐波那契螺旋以及环形线圈.相关研究为生物小分子的多级手性自组装提供了新的见解,可以促进相关材料在手性光学和不对称合成中的应用.
作者
Yuefei Wang
Dongzhao Hao
Jiayu Liu
Qing Li
Zixuan Wang
Xi Rong
Wei Qi
Rongxin Su
Zhimin He
王跃飞;郝东昭;刘佳羽;李清;王子瑄;荣喜;齐崴;苏荣欣;何志敏(State Key Laboratory of Chemical Engineering,School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China;Collaborative Innovation Center of Chemical Science and Engineering(Tianjin),Tianjin 300072,China;Tianjin Key Laboratory of Membrane Science and Desalination Technology,Tianjin University,Tianjin 300072,China)
基金
supported by the National Natural Science Foundation of China(21621004 and 22078239)
Tianjin Development Program for Innovation and Entrepreneurship(2018)
the State Key Laboratory of Chemical Engineering(SKL-Ch E-20Z04 and SKL-Ch E-21T03)。
