摘要
慢性肾衰竭(chronic renal failure,CRF)正成为全球性的社会问题,延缓其进展具有重要的现实意义。CRF可导致肠道菌群紊乱,破坏肠黏膜屏障,进一步推进慢性肾脏病进展,因此国外学者提出了“肠-肾轴”理论,将益生菌、益生元、炭吸附剂、中医灌肠疗法应用于慢性肾衰竭,靶向调节“肠-肾轴”,开启了从“肠”治疗慢性肾衰竭的新纪元。文章基于肠-肾轴对中西医从“肠”论治慢性肾衰竭相关研究进展进行综述,以期为治疗慢性肾衰竭提供新的策略及理论支持。
Chronic renal failure(chronic renal failure,CRF)is becoming a global social problem,and delaying its progress has important practical significance.CRF can cause intestinal flora disorder,destroy the intestinal mucosal barrier,and further promote the progress of chronic kidney disease.Therefore,foreign scholars have proposed the"gut-renal axis"theory,which applies probiotics,prebiotics,carbon adsorbents,and traditional Chinese medicine enema therapy.Chronic renal failure targets the regulation of the"intestine-renal axis",opening a new era in the treatment of chronic renal failure from the"intestine".Based on the intestine-renal axis,this article reviews the research progress related to the treatment of chronic renal failure in traditional Chinese and western medicine from the"intestine"theory,in order to provide new strategies and theoretical support for the treatment of chronic renal failure.
作者
崔移明
彭贵军
胡心
CUI Yiming;PENG Guijun;HU Xin(Henan University of Traditional Chinese Medicine,Zhengzhou 450000,Henan,China;The First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,Henan,China)
出处
《实用中医内科杂志》
2022年第10期55-57,共3页
Journal of Practical Traditional Chinese Internal Medicine
基金
河南省中医药科学研究专项(2018JDZX016)。
关键词
慢性肾衰竭
肠道微生物
肠-肾轴
chronic renal failure
intestinal microbes
intestine-renal axis
