摘要
下丘脑是人体重要的内分泌中枢,其通过分泌激素维持人体内环境稳定,并发挥神经-内分泌功能。作为内分泌系统的“启动器”,下丘脑的不同功能区含有多种神经分泌细胞,负责分泌不同的激素。下丘脑及其邻近组织起源的肿瘤,包括神经节细胞瘤、神经细胞瘤、胶质瘤、错构瘤、生殖细胞瘤等,通过占位效应、异常分泌激素等方式,对下丘脑或垂体的激素分泌产生影响,从而导致多种复杂的临床症候群。本文围绕近年来影响下丘脑激素分泌的肿瘤的相关特征及研究进展综述如下。
Hypothalamus is the center of endocrine for human body,which is crucial to homeostasis and plays an irreplaceable role in regulating neuroendocrine function by secreting hypothalamic hormones.As the“initiator”of endocrine system,different functional areas of hypothalamus contain various neurosecretory cells responsible for the secretion of different hormones.Tumors of hypothalamic and adjacent tissue origin,including ganglion cell tumors,neuroblastomas,gliomas,malignant tumors and germ cell tumors,affect hormonal secretion in the hypothalamus or pituitary gland through occupying effects and abnormal secretion of hormones,resulting in a variety of complex clinical syndromes.In recent years there has been some research into tumors affecting hypothalamic hormone secretion,which is briefly reviewed here.
作者
冯添顺
朱先理
王守森
Feng Tianshun;Zhu Xianli;Wang Shousen(Department of Neurosurgery,Dongfang Affiliated Hospital of Xiamen University(the 900th Hospital of Joint Logistics Team),Fuzhou 350025,China;Department of Neurosurgery,Sir Run Run Hospital,Medical College,Zhejiang University,Hangzhou 310016,China)
出处
《中华脑科疾病与康复杂志（电子版）》
2022年第3期183-186,共4页
Chinese Journal of Brain Diseases and Rehabilitation（Electronic Edition）
关键词
下丘脑
肿瘤
激素分泌
治疗策略
Hypothalamus
Tumors
Hormonal secretion
Treatment strategies
