摘要
目的:比较应用飞秒激光制瓣准分子激光原位角膜磨镶术(FS-LASIK)与750Hz切削频率和智能脉冲技术(SPT)的经上皮准分子激光屈光性角膜切削术(TransPRK)矫正中度近视的临床效果。方法:采用非随机前瞻性队列研究。纳入FS-LASIK治疗的患者48例90眼和TransPRK治疗的患者47例90眼。所有眼睛都是中度近视(等效球镜度-3.00~-6.00D)。FS-LASIK和TransPRK均由Schwind Amaris 750S准分子激光器进行。分别于术前及术后6mo对视力、等效球镜度及各项角膜高阶像差等变量进行分析,评估手术疗效。结果:术后6mo,FS-LASIK和TransPRK术后等效球镜度呈正视并相对稳定。术前和术后两组间术眼SE比较均无差异(P>0.05)。术后6mo,FS-LASIK组和TransPRK组患者的总高阶像差、球差及垂直彗差均较术前明显增加(均P<0.001),且FS-LASIK组患者的总高阶像差及垂直彗差高于TransPRK组(均P<0.001)。术后6mo,FS-LASIK组和TransPRK组平均疗效指数分别为1.054±0.172和1.082±0.147(t=-0.755,P=0.459)。术后6mo,FS-LASIK组平均安全性指数为1.009±0.114,明显低于TransPRK组的1.124±0.213(t=-2.322,P=0.033)。结论:FS-LASIK和SPT引导的TransPRK术后远期视力均较好。FS-LASIK组患者的总高阶像差及垂直彗差高于TransPRK组,且FS-LASIK安全性指数低于TransPRK。
AIM:To compare the clinical effect of femtosecond-assisted laser in situ keratomileusis(FS-LASIK)and trans-epithelial photorefractive keratectomy(TransPRK)using 750Hz ablation frequency and smart pulse technology(SPT)in the correction for moderate myopia.METHODS:A non-randomised,prospective cohort study was conducted on the included 48 patients(90 eyes)treated with FS-LASIK and 47 patients(90 eyes)treated with TransPRK.All eyes were moderate myopia(spherical equivalence-3.00~-6.00D).Both FS-LASIK and TransPRK were performed by Schwind Amaris 750S excimer laser.Visual acuity,refraction and corneal high order aberration were analyzed before and at 6mo after surgery,respectively,to evaluate the surgical efficacy.RESULTS:The diopters at 6mo after the surgery of FS-LASIK and TransPRK were emmetropic and relatively stable.There was no significant difference in preoperative and postoperative SE between the two groups(P>0.05).The total high order aberration,spherical aberration,and vertical coma at 6mo after surgery in the FS-LASIK group and TransPRK group were significantly higher than those before surgery(all P<0.001),and the total high order aberration and vertical coma in the FS-LASIK group were higher than those in the TransPRK group(all P<0.001).The mean validity index at 6mo after surgery was 1.054±0.172 and 1.082±0.147(t=-0.755,P=0.459)in the FS-LASIK group and TransPRK group,respectively.Moreover,the mean safety index of the FS-LASIK group was 1.009±0.114 at 6mo after surgery,which was significantly lower than 1.124±0.213 of the TransPRK group(t=-2.322,P=0.033).CONCLUSION:Both FS-LASIK and SPT-guided TransPRK had better postoperative long-term vision.The total high order aberration and vertical coma of patients in the FS-LASIK group were higher than those in the TransPRK group,and the safety index of FS-LASIK was lower than that in the TransPRK group.
作者
何之城
王亚茹
王勇
廖荣丰
Zhi-Cheng He;Ya-Ru Wang;Yong Wang;Rong-Feng Liao(Department of Ophthalmology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui Province,China;Department of Ophthalmology,Anhui Provincial No.2 People's Hospital,Hefei 230041,Anhui Province,China)
出处
《国际眼科杂志》
CAS
北大核心
2022年第12期2054-2057,共4页
International Eye Science
