摘要
肝小静脉闭塞症(HVOD)为肝内中央静脉、小叶下静脉管腔狭窄、闭塞所导致的窦后性门脉高压症。其发病率较低,在我国主要以口服含吡咯生物碱的植物后并发HVOD为主,临床上往往采用排除性诊断,肝穿刺活检为诊断本病的“金标准”。本文主要介绍HVOD的定义、病因、发病机理、病理表现、诊断方法及治疗策略的选择等。
Hepatic venule occlusive disease(HVOD)is a posterior sinus portal hypertension caused by the stenosis and occlusion of the central hepatic vein and sublobular vein.Its incidence is low,mainly oral plants containing pyrrole alkaloids and complications of HVOD in our country,clinical diagnosis of exclusion is often used,liver biopsy as the“gold standard”in the diagnosis of this disease.This paper mainly introduces the definition,etiology,pathogenesis,pathological manifestations,diagnostic methods and treatment strategies of HVOD.
作者
尚艺伟
李瑞军
SHANG Yiwei;LI Ruijun(Department of Gastroenterology and Intervention,Xi'an International Medical Center Hospital,Xi'an 710000)
关键词
肝内小静脉闭塞症
吡咯生物碱
研究现状
Small hepatic vein occlusion
Pyrrole alkaloid
Research Stat us quo
