摘要
目的:分析磁共振灌注加权成像(MR-PWI)参数评估子宫腺肌症不孕患者子宫内膜容受性价值。方法:回顾性收集本院2019年6月-2021年6月收治的子宫腺肌症不孕患者53例为不孕组及生育功能正常的同龄女性50例为对照组,均在月经周期19~22d行MRI灌注成像,记录子宫内膜及内膜下灌注参数[正性增强积分(PEI)、最大增强线性斜率(MSI)、平均强化时间(MTE)],分析不孕组子宫MRI扫描特点及子宫内膜及内膜下血流灌注参数水平。结果:不孕组53例中33例为弥漫性子宫腺肌症,T2WI扫描中结合带呈弥漫性均匀或不均匀增厚,结合带厚度(29.66±3.16mm)较对照组(10.06±1.74mm)增厚(P<0.001),共发现42个病灶,病灶在T1WI扫描中均呈等信号,T2WI扫描中呈低信号,内见散在点状高信号;20例为局限性子宫腺肌症,患者子宫体部或底部局限性增大,相应部位结合带增厚,结合带厚度(22.39±3.74mm)较对照组增厚(P<0.001),共发现27个病灶,T1WI上呈等信号,T2WI上呈与结合带信号相似的肿块影。不孕组子宫体积较对照组增大,子宫内膜厚度较对照组变薄,子宫内膜MR-PWI灌注参数PEI、MSI水平低于照组,MTE水平高于对照组,子宫内膜下MR-PWI灌注参数PEI、MSI水平低于对照组(均P<0.05)。相关性分析,不孕组子宫内膜厚度与其内膜MR-PWI灌注参数PEI及MSI均呈正相关(P<0.05),与MTE间无相关性(P>0.05)。结论:MR-PWI血流灌注参数可作为子宫腺肌病不孕患者胚胎种植预后的辅助判断指标。
Objective:To evaluate the value of magnetic resonance-perfusion weight imaging(MR-PWI)parameters in the assessment of endometrial receptivity of infertility women with adenomyosis.Methods:53 infertility women with adenomyosi from June 2019 to June 2021 were collected in study group retrospectively.50 normal women with the same age and normal reproductive function were selected in control group during the same period.MRI perfusion imaging was performed for the women in the two groups during the 19th-22nd days of menstrual cycle.The endometrial and subendometrial perfusion parameters,such as positive enhancement integral(PEI),maximum slope of increase(MSI),and mean time to enhance(MTE)of the women in the two groups were recorded.The MRI features and the perfusion parameters of endometrial and subendometrial blood flow of the women in the study group were analyzed.Results:There were 33 cases with diffuse adenomyosis in these 53 women in the study group,and the T2WI scan showed that the diffuse homogeneous or uneven thickening of uterine junctional zone in these 33 women.The thickness of uterine junctional zone(29.66±3.16 mm)of the women in the study group was significantly thicker than that(10.06±1.74mm)of the women in the control group(P<0.001).A total of 42 lesions of the women in the study were found,which showed middle intensity of T1WI sequences,and hypointensity with scattered dot-like high signal inside of T2WI sequences.There were 20 cases with localized adenomyosis in the study group,and these women had limited enlargement of the body or bottom of the uterus and had thickened junctional zone in the localized adenomyosis.The thickness of uterine junctional zone(22.39±3.74mm)of the women in the study group was significantly thicker than that of the women in the control group(P<0.001).27 lesions in these 20 cases with localized adenomyosis were identified,which showed the middle intensity of T1WI and a mass shadow similar to the signal of the junctional zone of T2WI.The uterine volume of the women in the st
作者
许保刚
魏刚
黄瑞瑜
贺朝
张婉
郭长义
张瑜
李斌
刘辉
XU Baogang;WEI Gang;HUANG Ruiyu;HE Chao;ZHANG Wan;GUO Changyi;ZHANG Yu;LI Bin;LIU Hui(Second Affiliated Hospital of Shaanxi University of Chinese Medicine,Shaanxi Province,712000)
出处
《中国计划生育学杂志》
2022年第11期2592-2595,2599,共5页
Chinese Journal of Family Planning
关键词
子宫腺肌症不孕
磁共振灌注加权成像参数
子宫内膜容受性
评估
Infertility wity adenomyosis
Magnetic resonance-perfusion weight imaging parameters
Endometrial receptivity
Evaluation
