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剖宫产术中辅助应用亚麻醉剂量艾司氯胺酮对术后镇痛药用量的影响 被引量:5

Effects of sub-anesthetic dose of esmketamine auxiliary used during cesarean section on the postoperative analgesics consumption
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摘要 目的:探讨剖宫产中对术后亚麻醉剂量艾司氯胺酮辅助应用镇痛药消耗量的影响。方法:随机选取本院2021年6月-2022年3月收治的剖宫产孕产妇78例,随机数字表法分为两组,观察组在对照组基础上加用亚麻醉剂量盐酸艾司氯胺酮。比较两组术后24、48h镇痛类纳布啡总消耗量、产妇完全苏醒时间、术后首次进食时间、麻醉生效及恢复时间、麻醉效果及不良反应。结果:对照组和观察组术后24h内纳布啡消耗量分别为(30.6±6.5mg、24.1±6.3mg),术后48h内纳布啡消耗量分别为(54.8±11.4mg、41.5±12.9mg),观察组均低于对照组(均P<0.05);两组麻醉生效时间以及恢复时间无差异(P>0.05);观察组麻醉总有效率(100.0%)高于对照组(87.2%),自控静脉镇痛(PCIA)泵停留时间、术后镇痛满意度均优于对照组,术后首次进食时间短于对照组(P<0.05),术后24h不良反应总发生率(7.7%)与对照组(10.3%)无差异(P>0.05)。结论:亚麻醉剂量艾司氯胺酮辅助应用能有效减少产妇术后镇痛药消耗量,提高术中镇痛及麻醉效果,增强围产期舒适度和满意度。 Objective:To investigate the effects of sub-anesthetic dose of esmketamine auxiliary used during cesarean section on the postoperative analgesics consumption.Methods:78 pregnant women who wanted cesarean section were randomly selected and were divided into two groups by random number table from June 2021 to March 2022.The women in the observation group were given sub-anesthetic dose of esmketamine auxiliaryly during cesarean section additionally.The total consumption of analgesic naborphine at 24 hours and 48 hours after operation,the time of complete awakening,the time of the first postoperative eating,the onset time of analgesia and the recovery time of anesthesia,the anesthetic effect,and the adverse reactions of the women were compared between the two groups.Results:The nalbuphine consumption within 24 and 48 hours after operation(30.6±6.5mg and 54.8±11.4mg)of the women in the observation group were significantly lower than those(24.1±6.3mg and 41.5±12.9mg)of the women in the control group(all P<0.05).The onset time and recovery time of anesthesia of the women had no significant differences between the two groups(P>0.05).The total effective rate of anesthesia(100.0%)of the women in the observation group was significantly higher than that(87.2%)of the women in the control group.The time of patient-controlled intravenous analgesia(PCIA)pump used and the postoperative analgesia satisfaction of the women in the observation group were significantly better than those of the women in the control group.The first time to eat after operation of the women in the observation group was significantly shorter than that of the women in the control group(P<0.05).The total incidence of adverse reactions(7.7%)of the women within 24 hours after operation had no significantly different from that(10.3%)of the women in the control group(P>0.05).Conclusion:The sub-anesthetic dose of esmketamine auxiliary used during cesarean section can effectively reduce the consumption of postoperative analgesics,improve the effect of analgesi
作者 王莎莎 张敏 WANG Shasha;ZHANG Min(Northwest Women's and Children's Hospital,Xi'an,Shaanxi Province,710061;Baoji Central Hospital,Shaanxi Province)
出处 《中国计划生育学杂志》 2022年第11期2485-2489,共5页 Chinese Journal of Family Planning
关键词 剖宫产术 艾司氯胺酮 亚麻醉剂量 镇痛药量 镇痛效果 麻醉效果 Cesarean section Esme ketamine Sub-anesthetic dose Analgesics dose Analgesics effect Anesthetic effect
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