摘要
目的对米索前列醇联合子宫收缩素预防产科出血进行临床研究,分析其临床疗效。方法随机抽取2018年1月至2019年12月在本院就诊的100例产妇,根据预防治疗措施的不同将其分为两组,其中对照组50例,采用缩宫素进行预防治疗;试验组50例,采用米索前列醇联合缩宫素进行预防治疗。观察两组患者在术后24 h内的出血量和发生的各种不良反应情况,并对比分析。结果试验组在术后24 h内的出血量均低于对照组,差异具有统计学意义(P<0.05);试验组在用药后的不良反应总发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论针对产妇在产科出血的临床治疗中,使用米索前列醇联合缩宫素对预防产科出血有较好的治疗效果,能有效减少出血量及不良反应总发生率,提升用药安全性。
Objective To study the clinical effect of misoprostol combined with oxytocin in the prevention of obstetric hemorrhage.Methods A total of 100 parturients were randomly selected from January 2018 to December 2019.According to the different preventive and therapeutic measures,they were divided into two groups,50 cases in the control group were treated with oxytocin,50 cases in the experimental group were treated with misoprostol and oxytocin.The amount of bleeding and adverse reactions of the two groups were observed and analyzed.Results The amount of bleeding in the experimental group was lower than that in the control group within 24 hours,the difference was statistically significant(P<0.05);the total incidence of adverse reactions in the experimental group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion In the clinical treatment of obstetric hemorrhage,misoprostol combined with oxytocin has a better therapeutic effect on the prevention of obstetric hemorrhage,can effectively reduce the amount of bleeding and the total incidence of adverse reactions,and improve the safety of medication.
作者
赵爽
ZHAO Shuang(Shenyang Dadong People's Hospital,Shenyang 110041,China)
出处
《中国医药指南》
2022年第31期108-110,共3页
Guide of China Medicine
