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立体定向微创软通道穿刺血肿引流术与开颅血肿清除术治疗高血压脑出血患者的疗效及对hs-CRP水平的影响 被引量:7

Analysis of the Effect of Stereotactic Minimally Invasive Soft Channel Puncture Hematoma Drainage and Craniotomy Hematoma Clearance on Patients with Hypertensive Intracerebral Hemorrhage and the Influence of hs-CRP Level
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摘要 目的研究立体定向微创软通道穿刺血肿引流术与开颅血肿清除术治疗高血压脑出血患者的疗效及对hs-CRP水平的影响。方法选取本院于2021年1月至2022年4月收治的高血压脑出血手术患者60例,按照随机数字表法分为对照组(30例)和观察组(30例),对照组患者采用开颅血肿清除术,观察组患者采用立体定向微创软通道穿刺血肿引流术,对比两组患者的围手术期指标、临床治疗效果、神经功能缺损及恢复评分、hs-CRP水平、生活质量评分、并发症情况。结果观察组患者术中出血量、手术时间低于对照组,有统计学意义(t=48.263、12.531,P<0.05)。观察组患者临床治疗效果高于对照组,有统计学意义(χ^(2)=11.065,P<0.05)。观察组患者治疗后NIHSS评分、mRS评分低于对照组,有统计学意义(t=6.760、5.843,P<0.05)。观察组与对照组患者治疗后hs-CRP均低于治疗前,且观察组患者治疗后hs-CRP低于对照组,有统计学意义(t=12.357、9.484、6.705,P<0.05)。观察组与对照组患者治疗后生活质量评分均高于治疗前,且观察组患者治疗后生活质量评分高于对照组,有统计学意义(t=23.408、17.635、11.026,P<0.05)。观察组患者并发症总发生率低于对照组,有统计学意义(χ^(2)=9.304,P<0.05)。结论立体定向微创软通道穿刺血肿引流术治疗高血压脑出血患者的疗效显著优于开颅血肿清除术,hs-CRP水平显著下降,可明显改善患者在围手术期指标水平、神经功能缺损、生活质量以及并发症情况。 Objective To study the effect of stereotactic minimally invasive soft channel puncture hematoma drainage and craniotomy hematoma clearance on patients with hypertensive intracerebral hemorrhage and the influence of hs-CRP level.Methods Sixty patients with hypertensive intracerebral hemorrhage who were treated in our hospital from January 2021 to April 2022 were selected and divided into control group(30 cases)and observation group(30 cases)according to the method of random number table.The patients in the control group with hypertensive intracerebral hemorrhage were treated with craniotomy hematoma removal,and the patients in the observation group with hypertensive intracerebral hemorrhage were treated with stereotactic minimally invasive soft channel puncture hematoma drainage.The perioperative indexes,clinical treatment effect,neurological deficit and recovery score,hs-CRP level,quality of life score,and complications of hypertensive intracerebral hemorrhage patients in the two groups were compared.Results The amount of intraoperative hemorrhage and operation time in the observation group were lower than those in the control group(t=48.263,12.531,P<0.05).The clinical treatment effect of hypertensive cerebral hemorrhage patients in the observation group was higher than that in the control group,with statistical significance(χ^(2)=11.065,P<0.05).NIHSS score and mRS score of patients with hypertensive intracerebral hemorrhage in the observation group after treatment were lower than those in the control group,with statistical significance(t=6.760,5.843,P<0.05).The hs-CRP of patients with hypertensive intracerebral hemorrhage in the observation group and the control group after treatment were lower than thoset before treatment,and the hs-CRP of patients with hypertensive intracerebral hemorrhage in the observation group after treatment was lower than that of the control group(t=12.357,9.484,6.705,P<0.05).The quality of life score of hypertensive intracerebral hemorrhage patients in the observation group and the con
作者 苏志民 张建王 SU Zhimin;ZHANG Jianwang(Department of Neurosurgery,Anxi County Hospital,Anxi 362400,China)
出处 《中国医药指南》 2022年第31期76-78,共3页 Guide of China Medicine
关键词 高血压脑出血 临床治疗效果 HS-CRP水平 并发症 Hypertensive intracerebral hemorrhage Clinical treatment effect hs-CRP level Complication
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