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产前超声对胎儿侧脑室增宽的判定及与新生儿早期神经发育的关系 被引量:6

Determination of Fetal Lateral Ventricle Dilatation by Prenatal Ultrasound and Its Relationship with Early Neonatal Neurodevelopment
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摘要 本文探究产前超声影像特征、侧脑室后角宽度与双顶径比值,对胎儿侧脑室增宽(VM)程度的判定价值及与新生儿早期神经发育的关系。选取120例胎儿VM孕妇作为研究对象,根据VM程度分为轻度组(n=61)、中度组(n=37)和重度组(n=22)。所有研究对象均行产前超声获得胎儿产前超声影像特征、侧脑室后角宽度与双顶径比值。结果显示,VM胎儿的产前超声影像特征为:随着VM程度增加,超声显示侧脑室增宽逐渐明显;重度组产前胎儿的侧脑室后角宽度与双顶径比值大于轻度组、中度组,中度组大于轻度组(P<0.05);产前侧脑室后角宽度与双顶径比值和VM程度呈正相关(P<0.05);早期神经发育异常新生儿产前侧脑室后角宽度与双顶径比值、侧脑室宽度均高于早期神经发育正常新生儿(P<0.05);产前侧脑室后角宽度与双顶径比值、侧脑室宽度与早期NBNA评分呈负相关(P<0.05);产前侧脑室后角宽度与双顶径比值联合侧脑室宽度预测新生儿早期神经发育异常的曲线下面积(AUC)为0.938。说明VM胎儿的产前超声影像特征、侧脑室后角宽度与双顶径比值可判定VM程度,且产前侧脑室后角宽度与双顶径比值和新生儿早期神经发育结局密切相关。 This article explored the prenatal ultrasound imaging features,the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter,its value in determining the degree of fetal lateral ventriculomegaly(VM),and its relationship with early neonatal neurodevelopment.A total of 120 pregnant women with fetal VM were selected as the research objects,and they were divided into mild group(n=61),moderate group(n=37)and severe group(n=22)according to the degree of VM.All subjects underwent prenatal ultrasound to obtain fetal prenatal ultrasound imaging characteristics,the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter.The results showed that the prenatal ultrasound imaging features of lateral VM fetuses were:as the degree of lateral VM increased,the ultrasound showed that the lateral ventricle widened gradually.The ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter of the fetal prenatal in the severe group was greater than that in the mild group and the moderate group,and the moderate group was greater than that in the mild group(P<0.05).The ratio of posterior horn width to biparietal diameter of prenatal lateral ventricle was positively correlated with the degree of lateral VM(P<0.05).The ratio of posterior horn width to biparietal diameter and width of lateral ventricle in neonates with early neurodevelopmental abnormality were higher than those in neonates with normal early neurodevelopment(P<0.05).The ratio of posterior horn width and biparietal diameter of prenatal lateral ventricle,lateral ventricle width and early NBNA score were negatively correlated(P<0.05).The area under the curve(AUC)of the ratio of prenatal posterior horn width to biparietal diameter combined with lateral ventricle width in predicting early neonatal neurodevelopmental abnormalities was 0.938.It indicated that the prenatal ultrasound imaging features of the fetus with lateral VM and the ratio of the width of the posterior horn of t
作者 吴俊莉 何志全 王开碧 熊荣勤 WU Junli;HE Zhiquan;WANG Kaibi;XIONG Rongqin(The Third Affiliated Hospital of Zunyi Medical University(The First People’s Hospital of Zunyi),Zunyi 563099,Guizhou,P.R.China;School of Preclinical Medicine of Zunyi Medical University,Zunyi 563003,Guizhou,P.R.China)
出处 《影像科学与光化学》 CAS 北大核心 2022年第6期1565-1569,共5页 Imaging Science and Photochemistry
关键词 胎儿 侧脑室增宽 产前超声 侧脑室后角宽度与双顶径比值 神经发育 fetus lateral ventriculomegaly prenatal ultrasound ratio of posterior horn width to biparietal diameter neurodevelopment
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