摘要
目的探讨超声下甲状腺结节内部粗大钙化和细小钙化在恶性甲状腺结节诊断中的临床意义.方法选择53例甲状腺结节患者为研究对象,以彩超下钙化灶直径2 mm为界进行分组,彩超下显示粗钙化(最小直径>2 mm)的甲状腺结节患者为对照组(n=30),彩超下显示微钙化(最大直径≤2 mm)的甲状腺结节患者为观察组(n=23),计算甲状腺结节伴有钙化灶对于甲状腺结节性质诊断的灵敏度、特异度、阳性预测值、阴性预测值,再计算粗钙化和微钙化二者对辅助诊断甲状腺结节的性质及差异.结果超声下结节钙化对于甲状腺癌诊断的灵敏度为53.85%(21/39),特异度为85.71%(12/14),阳性预测值为91.30%(21/23),阴性预测值为40.00%(12/30),诊断价值较高.微钙化对于甲状腺癌的检出率为91.3%,粗钙化对于甲状腺癌的检出率为60.0%(P﹤0.05).结论甲状腺结节伴有钙化灶对于恶性结节的诊断具有临床意义.
Objective To study the clinical significance and difference between coarse calcification and fine calci-fication in thyroid nodules under ultrasound in the diagnosis of malignant thyroid nodules.Method Fifty-three patients with thyroid nodules were selected as the research subjects.Patients with preoperative calcification under color Doppler ultrasonography and supported by postoperative pathological results were grouped with the calci-fication diameter of 2 mm under color Dopplar ultrasound.Thyroid nodules with coarse calcification(minimum diameter>2 mm)under color Dopplar ultrasound were classified as the control group(n=30).Thyroid nodules with microcalcification(maximum diameter≤2 mm)under color Dopplar ultrasound were classified into the observation group(n=23).The sensitivity,specificity,positive predictive value and negative predictive value of thyroid nodules with calcification for the diagnosis of the nature of thyroid nodules were calculated to study the significance of calcification for clinical diagnosis.The differences between the coarse calcification and the microcalcification in the nature of the auxiliary diagnosis of thyroid nodules is calculated.Results The sensitivity of ultrasonic calcification of lower nodules in the diagnosis of thyroid cancer was 53.85%(21/39),the specificity was 85.71%(12/14),the positive predictive value was 91.30%(21/23)and the negative predictive value was 40.00%(12/30),it is of great diagnostic value.The detection rate of microcalcification for thyroid cancer was 91.3%,the detection rate of coarse calcification for thyroid cancer was 60.0%(P<0.05).Conclusion Thyroid nodules with calcifications have clinical significance for the diagnosis of malignant nodules.
作者
伏彤
陈治龙
李清华
FU Tong;CHEN Zhilong;LI Qinghua(Affiliated Hospital of Beihua University,Jilin 132011,China)
出处
《北华大学学报（自然科学版）》
CAS
2022年第5期647-649,共3页
Journal of Beihua University（Natural Science）
关键词
甲状腺结节
钙化灶
病理
thyroid nodules
calcification stove
pathology
