摘要
目的:研究桃红四物汤加减治疗四肢骨折患者的临床效果。方法:选取2018年1月-2021年1月漳浦县医院收治的80例四肢骨折患者作为研究对象,采用随机数字表法分为试验组和对照组,各40例。对照组采用手术治疗,试验组在对照组基础上加用桃红四物汤加减治疗。比较两组的临床症状、康复指标、血清炎症因子水平、凝血功能因子水平及不良反应发生率。结果:术后14 d试验组的疼痛评分、肿胀评分低于对照组,差异有统计学意义(P<0.05);试验组骨折愈合时间、患肢肿胀完全消除时间早于对照组,差异有统计学意义(P<0.05);术后14 d试验组的血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白介素-8(IL-8)水平低于对照组,差异有统计学意义(P<0.05);术后14 d试验组的血浆凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)长于对照组,纤维蛋白原(FIB)水平低于对照组,差异有统计学意义(P<0.05);术后14 d内两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:桃红四物汤加减治疗四肢骨折患者能有效缩短患者骨折愈合时间,促使患者疼痛、肿胀等症状快速缓解,同时对改善患者血清炎症因子水平和凝血功能因子水平均有积极作用,患者安全性良好,值得临床推广。
Objective:To study the effect of Taohong Siwu Decoction modified on patients with limb fracture.Method:A total of 80 patients with limb fractures treated in Zhangpu County Hospital from January 2018 to January 2021 were selected as the research objects.According to the method of random number table,they were divided into experimental group and control group,40 cases in each group.The control group was treated with surgery,while the experimental group was treated with Taohong Siwu Decoction modified on the basis of the control group.The clinical symptoms,rehabilitation indicators,serum inflammatory factors levels,coagulation factor levels and the incidence of adverse reactions were compared between the two groups.Result:On the 14th day after operation,the pain score and swelling score in the experimental group were lower than those in the control group,and the differences were statistically significant (P<0.05).The healing time of fracture and the complete elimination time of swelling of the affected limbs in the experimental group were earlier than those in the control group,and the differences were statistically significant (P<0.05).On the 14th day after operation,the levels of serum C-reactive protein (CRP),tumor necrosis factor-α (TNF-α) and interleukin-8 (IL-8) in the experimental group were significantly lower than those in the control group (P<0.05).On the 14th day after operation,the plasma prothrombin time (PT) and activated partial thromboplastin time (APTT) in the experimental group were longer than those in the control group,and the level of fibrinogen (FIB) was lower than that in the control group,the differences were statistically significant (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups within 14 days after operation (P>0.05).Conclusion:The Taohong Siwu Decoction modified in the treatment of patients with limb fracture can effectively shorten the time of fracture healing,promote the rapid relief of pain,swelling and other symptoms,and pla
作者
黄凯明
张晓农
李曼彬
HUANG Kaiming;ZHANG Xiaonong;LI Manbin(Zhangpu County Hospital,Zhangpu 363200,China)
出处
《中外医学研究》
2022年第30期137-140,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
四肢骨折
桃红四物汤
治疗效果
炎症因子
凝血功能
Limb fracture
Taohong Siwu Decoction
Therapeutic effect
Inflammatory factor
Coagulation function
