摘要
目的:了解老年人群的常见疾病、常用药物及多重用药情况,为制定老年人群的药物重整策略提供依据。方法:调取于3家三级医院门诊就诊的地方和军人老年患者的口服药物信息,另采用问卷调查法调研上海市干休所老干部用药信息,分析上述各医院门诊地方和军人老年患者以及干休所老干部的患病情况和用药情况。结果:最终纳入分析的15 356例患者中,A医院地方患者459例,B医院地方患者598例,C医院地方患者13 213例,C医院军人患者366例,干休所老干部720例。干休所老干部的平均年龄为(84.55±10.09)岁,平均患病种数为(5.78±3.34)种,平均用药种数为(6.43±3.80)种,均高于其他老年患者,差异均有统计学意义(P<0.01)。A医院地方患者、B医院地方患者、C医院地方患者、C医院军人患者和干休所老干部中,服用5种及以上药物者分别占6.32%(29/459)、10.37%(62/598)、13.04%(1 723/13 213)、60.93%(223/366)和68.61%(494/720)。除70岁以下干休所老干部外,其他不同特征干休所老干部的多重用药率均>50%,且年龄越大、文化程度越低、睡眠质量越差者多重用药率越高。干休所老干部以患慢性疾病为主,不同疾病组、使用不同药品组患者的平均用药种数均>7种,除骨质疏松疾病组(56.04%,181/323)外,其他组患者的多重用药率均>70%,多重用药现象普遍存在于常见的每种慢性疾病及其常用的治疗药物。结论:老年人群多病共存、多重用药现象严重,门诊处方干预不能有效解决多重用药问题,需要制定适用于老年人群的药物重整策略。
OBJECTIVE: To investigate the common diseases, commonly used drugs and polypharmacy in the elderly, so as to provide basis for the formulation of drug rearrangement strategies in the elderly. METHODS: The oral drug information of local and military patients of three tertiary hospitals was collected, the drug information of retired officers living in sanatoriums in Shanghai was investigated by questionnaire survey method, and the disease and medication of outpatients and retired officers were analyzed. RESULTS: A total of 15 356 patients were enrolled in the analysis, including 459 local patients in hospital A, 598 local patients in hospital B, 13 213 local patients in hospital C, 366 military patients in hospital C, and 720 retired officers in sanatoriums. The mean age(84.55±10.09) years, the mean number of diseases(5.78±3.34) categories, and the mean number of drugs(6.43±3.80) categories of retired officers in sanatoriums were higher than those of other elderly patients, with statistically significant differences(P<0.01). Among local patients in hospital A, local patients in hospital B, local patients in hospital C, military patients in hospital C, and anretired officers in sanatoriums, those taking 5 or more drugs accounted for 6.32%(29/459), 10.37%(62/598), 13.04%(1 723/13 213), 60.93%(223/366) and 68.61%(494/720).In addition to the old cadres under the age of 70, the prevalence of polypharmacy in retired officers with other different characteristics were more than >50%,and the polypharmacy was remarkably serious among the elderly with older age, lower education and worse sleep quality. Retired officers were mainly suffering from chronic diseases, and the mean number of medications used by patients in different disease groups and drug groups with various drugs was more than 7. Except for the osteoporosis disease group(56.04%, 181/323), the prevalence of polypharmacy used by patients in other groups was >70%, and the phenomenon of polypharmacy was prevalent for each common chronic disease and its commonly us
作者
邓敏
尹畅
吴含达
王雪
拓西平
周全
蔡全才
陈礼治
王卓
DENG Min;YIN Chang;WU Handa;WANG Xue;TUO Xiping;ZHOU Quan;CAI Quancai;CHEN Lizhi;WANG Zhuo(Dept.of Pharmacy,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;College of Life Sciences and Biopharmaceuticals,Shenyang Pharmaceutical University,Shenyang 110016,China;College of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University,Nanjing 211198,China;Geriatrics Center of Naval Medical University,Shanghai 200433,China;Clinical Teaching and Training Center,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;Clinical Epidemiology Research Center,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China)
出处
《中国医院用药评价与分析》
2022年第10期1251-1254,1258,共5页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
国家自然科学基金项目(No.81870520)
军队后勤科研项目保健专项(No.19BJZ01)。
关键词
老年人
多重用药
药物重整
问卷调查
Elderly patients
Polypharmacy
Medication reconciliation
Questionnaire
