摘要
目的探究衰弱老年患者患有胃癌需要开展胃癌根治术时,为其实施瑞马唑仑复合瑞芬太尼麻醉的效果,重点不同麻醉方案的实施效果、安全性以及对患者身心的影响。方法采用随机数表法,将随机选取该院2021年1月—2022年1月收治并纳入研究的40例胃癌根治术衰弱老年患者分组,对照组(20例,咪达唑仑复合瑞芬太尼麻醉),观察组(40例,瑞马唑仑复合瑞芬太尼麻醉),分析不良反应、麻醉效果、手术情况和患者身心状况。结果观察组术中不良反应总发生率为5.00%少于对照组的40.00%,差异有统计学意义(χ^(2)=5.161,P=0.023);观察组麻醉恢复室总不良反应率低于对照组,差异有统计学意义(χ^(2)=6.144,P=0.013);观察组麻醉后起效所用时间为(42.64±10.98)s、清醒所用时间为(22.83±4.37)s优于对照组(54.91±10.31)s,(20.43±4.07)s,差异有统计学意义(t=3.643、1.797,P<0.05)。观察组手术情况指标、身心状况指标也优于对照组,差异有统计学意义(P<0.05)。结论相较于对照组实施的咪达唑仑复合瑞芬太尼麻醉方案,瑞马唑仑复合瑞芬太尼麻醉效果更优异,手术阶段和麻醉恢复室出现不良反应例数较少,麻醉起效快且药效停留时间长,从而使得手术开展更加顺利,手术效果明显提升,促使患者身体素质提高,不良情绪好转,研究有较大价值。
Objective To explore the effect of remazolam combined with remifentanil anesthesia for frail elderly pa‐tients with gastric cancer who need radical gastrectomy for gastric cancer,focusing on the implementation effect,safety,and physical and mental impact of different anesthesia programs.Methods Using the random number table method,randomly selected 40 elderly patients with debilitated gastric cancer who were admitted to the hospital and included in the study from January 2021 to January 2022 were divided into groups,the control group(20 cases,mid‐azolam combined with remifentanil anesthesia),observation group(40 cases,remazolam combined with remifentanil anesthesia),the adverse reactions,anesthesia effect,operation conditions and physical and mental conditions of the patients were analyzed.Results The total incidence of intraoperative adverse reactions in the observation group was 5.00%,which was significantly lower than that in the control group(40.00%),the difference was statistically signifi‐cant(χ^(2)=5.161,P·=0.023);the total rate of adr in anesthesia recovery room in the observation group was lower than that in the control group,and the difference was statistically significant(χ^(2)=6.144,P=0.013);the onset time after an‐esthesia in the observation group was(42.64±10.98)s,and the time it took to wake up was(22.83±4.37)s,which was better than that in the control group(54.91±10.31)s,(20.43±4.07)s,the difference was statistically significant(t=3.643,1.797,P<0.05).The operation condition indexes and physical and mental condition indexes of the observation group were also better than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with the midazolam combined with remifentanil anesthesia program implemented in the con‐trol group,the anesthesia effect of remazolam combined with remifentanil was better,and the number of adverse reac‐tions in the operation stage and anesthesia recovery room was less.The onset of anesthesia is fast and the dru
作者
车呈凯
CHE Chengkai(Department of Anesthesiology,Zibo Hospital,Shandong Yiyang Health Group,Zibo,Shandong Province,255120 China)
出处
《中外医疗》
2022年第18期109-112,共4页
China & Foreign Medical Treatment
关键词
瑞马唑仑复合瑞芬太尼
麻醉
衰弱老年
胃癌根治术
术中不良反应
麻醉恢复室不良反应
麻醉效果
手术情况
身心状况
Remazolam combined with remifentanil
Anesthesia
Frail elderly
Radical gastrectomy
Intraoperative adverse reactions
Adverse reactions in anesthesia recovery room
Anesthesia effect
Surgical situation
Physical and mental status
