摘要
目的探讨临床药师通过问题导向型的药学干预在乙型肝炎病毒(HBV)感染患者中的应用并分析其应用价值。方法研究中选取2019年4月~2020年11月南通大学附属南通第三医院肝病科收治的188例HBV感染患者,2019年4月~2020年1月的94例患者作为对照组,2020年2月~2020年11月的94例患者作为观察组,对照组患者在常规治疗的基础上给予常规的临床药学干预,观察组患者则给予问题导向型的临床药学干预,干预后,比较两组患者自我管理能力情况、抑郁与焦虑评分情况、用药依从性及生活质量得分情况。结果接受不同模式的药学干预12周后,观察组患者的生活、情绪、症状与自我效能管理的得分均显著高于对照组患者(P<0.05);干预前两组患者的SDS、SAS得分情况比较差异无统计学意义(P>0.05),不同药学模式干预后,同组相比较,均较干预前显著改善(P<0.05),且观察组显著低于对照组(P<0.05);观察组患者的总依从情况88.30%显著优于对照组患者的72.34%(P<0.05);观察组患者生理功能、躯体疼痛、社会职能及心理状态的评分均高于对照组患者(P<0.05)。结论在HBV感染患者中应用问题导向型的临床药学干预,能显著改善患者的负面情绪,提高患者自我管理能力与用药依从性,并大幅度改善患者的生活质量。
Objective To explore the role of clinical pharmacists in hepatitis B virus through problem-oriented pharmaceutical intervention Methods 188 patients with HBV infection treated in the department of liver diseases of Nantong Third Hospital Affiliated to Nantong University from April 2019 to November 2020,94 patients from April 2019 to January 2020 were selected as the control group,and 94 patients from February 2020 to November 2020 were selected as the observation group.The patients in the control group were given routine treatment on the basis of routine treatment after the intervention,the patients in the observation group were given problem-oriented clinical pharmaceutical intervention.After the intervention,the self-management ability,depression and anxiety scores,medication compliance and quality of life scores of the two groups were compared.Results After receiving different modes of pharmaceutical intervention for 12 weeks,the life,emotion and the scores of symptoms and self-efficacy management were significantly higher than those in the control group(P<0.05);the comparison of SDS and SAS scores between the two groups before the intervention showed no statistical significance(P>0.05).After the intervention of different pharmaceutical modes,compared with the same group before the intervention,they were significantly improved(P<0.05),but the observation group was significantly lower than that in the control group(P<0.05);the total compliance of 88.30% of patients in the observation group was significantly better than 72.34% of patients in the control group(P<0.05);the scores of physiological function,physical pain,social function and psychological state of patients in the observation group were higher than those in the control group(P<0.05).Conclusion The application of problem-oriented clinical pharmaceutical intervention in patients with hepatitis B virus(HBV)infection can significantly improve the negative emotions of patients,improve their self-management ability and medication compliance,and greatly impr
作者
陈敏
乔进
朱勇根
CHEN Min;QIAO Jin;ZHU Yong-gen(Department of pharmacy,Nantong Third Hospital Affiliated to Nantong University,Nantong 226006,China;不详)
出处
《中国处方药》
2022年第10期34-36,共3页
Journal of China Prescription Drug
基金
南通卫健委青年医学人才科研基金项目(WR2017011)。
关键词
乙型肝炎病毒
药学干预
临床药学
问题导向
用药依从性
Hepatitis B virus
Pharmaceutical intervention
Clinical pharmacy
Problem orientation
Medication compliance
