摘要
特应性皮炎(AD)是一种以剧烈瘙痒和易于复发为特点的慢性炎症性皮肤病。近年来的研究认为,肠道菌群失衡在AD的发生发展中发挥着重要作用,中药可通过调节肠道菌群参与免疫应答、代谢、神经内分泌调控等多种途径来发挥治疗作用。本文在介绍肠道菌群在AD发病机制中作用的基础上,综述中药通过调控肠道菌群治疗AD的研究进展,以期为靶向调节肠道菌群治疗AD的新药研发和预防提供依据。
Atopic dermatitis(AD)is a chronic inflammatory skin disease characterized by severe itching and easy recurrence.In recent years,studies have suggested that the imbalance of intestinal flora plays an important role in the occurrence and development of AD.Traditional Chinese medicine plays a therapeutic role by regulating intestinal flora to participate in immune response,metabolism,neuroendocrine regulation,and other ways.Based on the introduction of the role of intestinal flora in the pathogenesis of AD,this paper reviews the research progress of traditional Chinese medicine in the treatment of AD by regulating intestinal flora,in order to provide a basis for the development of new drugs targeting intestinal flora to treat and prevent AD.
作者
马雪宁
杨素清
袁锐
MA Xuening;YANG Suqing;YUAN Rui(Department of Dermatology,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin 150040,China)
出处
《中国医药导报》
CAS
2022年第29期42-45,共4页
China Medical Herald
基金
黑龙江省中医药管理局省级名中医专家传承工作室建设项目(G20191503)。
关键词
特应性皮炎
肠道菌群
中药
综述
Atopic dermatitis
Intestinal flora
Traditional Chinese medicine
Review
