摘要
目的 探讨糖尿病相关心理痛苦在成人1型糖尿病(T1DM)患者低血糖恐惧与生活质量之间的中介作用。方法 采用便利抽样法选取363例成人T1DM患者作为研究对象,采用自制一般情况调查表、中文版低血糖恐惧-忧虑量表(CHFSⅡ-WS)、糖尿病相关问题量表(PAID-5)、中文版胰岛素治疗患者生活质量量表(ITR-QOL-CV)进行调查。比较不同特征T1DM患者的生活质量得分,并分析3种量表得分之间的相关性,通过建立结构方程模型,分析糖尿病相关心理痛苦在低血糖恐惧与生活质量间的中介作用。结果 363例患者的CHFSⅡ-WS、PAID-5、ITR-QOL-CV得分分别为(7.96±5.97)分、(48.62±27.72)分、(88.79±16.22)分。不同病程、家庭月收入、治疗方式、并发症发生情况T1DM患者的ITR-QOL-CV得分差异有统计学意义(均P<0.05)。T1DM患者CHFSⅡ-WS得分与ITR-QOL-CV得分呈负相关,CHFSⅡ-WS得分与PAID-5得分呈正相关,PAID-5得分与ITR-QOL-CV得分呈负相关(均P<0.05)。糖尿病相关心理痛苦在低血糖恐惧与生活质量间发挥部分中介效应,占总效应的28.52%。结论 糖尿病相关心理痛苦、低血糖恐惧和生活质量三者间存在相关性,糖尿病相关心理痛苦在低血糖恐惧与生活质量间具有部分中介作用。在临床工作中要尽早识别具有低血糖恐惧及心理痛苦的患者,采取针对性的干预措施,以提高患者生活质量。
Objective To explore the mediating effect of diabetes-related psychological distress between fear of hypoglycemia and quality of life in adult patients with type 1 diabetes mellitus(T1DM).Methods A total of 363 adult patients with T1DM were selected by the convenience sampling method.The patients were investigated by the self-made general condition questionnaire,Chinese Version Hypoglycemia Fear SurveyⅡ-Worry Scale(CHFⅡ-WS),5-Item Problem Areas in Diabetes Survey(PAID-5),and Insulin Therapy Related Quality of Life Measure Questionnaire-Chinese Version(ITR-QOL-CV).The score of quality of life was compared between T1DM patients with different characteristics,and the correlation between the 3 scale scores was analyzed.The mediating effect of diabetes-related psychological distress between fear of hypoglycemia and quality of life was analyzed through establishing structural equation model.Results The scores of 363 patients in CHFSⅡ-WS,PAID-5,and ITR-QOL-CV were(7.96±5.97),(48.62±27.72),and(88.79±16.22),respectively.There were statistically significant differences in ITR-QOL-CV score between T1DM patients with different disease courses,family monthly incomes,therapeutic methods,and the occurrences of complications(all P<0.05).The CHFSⅡ-WS score of T1DM patients negatively correlated with the ITR-QOL-CV score,whereas positively correlated with the PAID-5 score,and the PAID-5 score negatively correlated with the ITR-QOL-CV score(all P<0.05).Diabetes-related psychological distress exerted a partial mediating effect between fear of hypoglycemia and quality of life,accounting for 28. 52% of the total effect.Conclusion Diabetes-related psychological distress,fear of hypoglycemia and quality of life are correlated,anddiabetes-related psychological distress exerts a partial mediating effect between fear of hypoglycemia and quality oflife. In clinical work,patients with hypoglycemia fear and psychological distress should be identified as soon as possible,and targeted intervention measures should be taken to improve
作者
王洪
朱敏
罗丹
于健
周美景
施云
张梅
袁翠萍
徐晶晶
WANG Hong;ZHU Min;LUO Dan;YU Jian;ZHOU Mei-jing;SHI Yun;ZHANG Mei;YUAN Cui-ping;XU Jing-jing(Department of Endocrinology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu,China;School of Nursing,Nanjing University Of Chinese Medicine,Nanjing 210023,Jiangsu,China)
出处
《广西医学》
CAS
2022年第17期2026-2030,2044,共6页
Guangxi Medical Journal
基金
江苏省人民医院临床能力提升工程项目(JSPH-NC-2020-8)
江苏省人民医院护理科研课题(YHK201738)。
关键词
糖尿病
1型
心理痛苦
低血糖恐惧
生活质量
中介效应
Diabetes mellitus
Type 1
Psychological distress
Fear of hypoglycemia
Quality of life
Mediating effect
