摘要
【目的】探讨血小板分布宽度(PDW)联合应激性血糖升高比值(SHR)对急性心肌梗死患者发生心力衰竭的预测价值。【方法】选取2018年1月至2020年1月本院收治的74例急性心肌梗死患者(观察组),另选取同期来院体检的68例健康者(对照组),比较观察组、对照组PDW和SHR。随访1年,统计急性心肌梗死患者心力衰竭发生率,比较急性心肌梗死发生心力衰竭与未发生心力衰竭患者临床特征,采用Logistic多元回归分析影响急性心肌梗死患者发生心力衰竭的相关因素,采用受试者工作特征曲线(ROC曲线)分析PDW、SHR预测急性心肌梗死患者发生心力衰竭的效能。【结果】观察组患者PDW、SHR均高于对照组,差异有统计学意义(P<0.05)。随访1年,急性心肌梗死患者心力衰竭发生率为28.38%。发生心力衰竭患者多支血管病变构成比及左心射血分数、PDW、SHR与未发生心力衰竭患者比较,差异均有统计学意义(P<0.05)。Logistic多因素回归分析显示,PDW、SHR、左心射血分数均是急性心肌梗死患者发生心力衰竭的独立危险因素(P<0.05);ROC曲线分析显示,PDW、SHR预测急性心肌梗死患者发生心力衰竭的最佳截断点分别为20.086%、1.250,二者联合的特异度和曲线下面积(AUC)分别为98.11%、0.889,均高于PDW、SHR单独预测。【结论】急性心肌梗死患者PDW、SHR均异常升高,PDW、SHR均是急性心肌梗死患者发生心力衰竭的独立危险因素,二者联合预测急性心肌梗死患者发生心力衰竭的价值较高。
【Objective】To explore the predictive power of platelet distribution width(PDW)combined with stress blood glucose increase ratio(SHR)for heart failure after acute myocardial infarction.【Methods】Seventy six patients with acute myocardial infarction admitted to the hospital from January 2018 to January 2020 were selected,and 68 healthy patients who came to the hospital for physical examination during the same period were selected.The PDW and SHR of patients with acute myocardial infarction and healthy people were compared,follow-up for 1 year after treatment,the incidence of heart failure in patients with acute myocardial infarction was counted.The clinical characteristics of patients with acute myocardial infarction with heart failure and without heart failure,Logistic multiple regression analysis was used to determine the factors affecting heart failure in patients with acute myocardial infarction,the receiver operator characteristic(ROC)curve was used to analyze the efficacy of PDW combined with SHR in predicting heart failure in patients with acute myocardial infarction.【Results】The PDW and SHR of patients with acute myocardial infarction were higher than those of healthy people(P<0.05).After 1 year of follow-up,the incidence of heart failure in patients with acute myocardial infarction was 28.38%.Compared with patients without heart failure,the composition ratio of multivessel disease and left ventricular ejection fraction,PDW,SHR of patients with heart failure were significantly different(P<0.05).Logistic multivariate regression analysis showed that PDW,SHR,and left ventricular ejection fraction were all independent risk factors for heart failure in patients with acute myocardial infarction(P<0.05).ROC curve analysis showed that the best cutoff points for PDW and SHR to predict the occurrence of heart failure in patients with acute myocardial infarction were 20.086%and 1.250,respectively.The specificity and AUC of the combination of PDW and SHR were 98.11%and 0.889,respectively,which were higher th
作者
黄佳雯
张美娟
周煜
HUANG Jia-wen;ZHANG Mei-juan;ZHOU Yu(Xi'an Hospital of Traditional Chinese Medicine,Xi'an Shaanxi 710016)
出处
《医学临床研究》
CAS
2022年第9期1291-1294,共4页
Journal of Clinical Research
基金
西安市卫生健康委员会科研项目(项目编号:2020yb28)。
