摘要
龋病是危害人类口腔健康的常见疾病之一,早期龋病指致龋菌形成牙菌斑产酸导致釉质表层下脱矿但表层完好未形成龋洞的部分龋损,局部用药能够控制早期龋病的发生、发展。本文通过检索国内外数据库相关文献,从氟化物及含氟制剂、抗生素和天然有效成分3个方面综合阐述早期龋病局部使用药物的作用原理、防龋效能和临床应用,归纳各类药物的优缺点,旨在强调龋病的危害性及局部用药防治早期龋病的重要性,为临床提供一定的参考。
Caries is a common disease that harms human oral health.Early caries refers to the partial caries lesions which result from the demineralization of enamel exposured to acid produced by plaque bacteria,while the surface layer is intact without the formation of caries.The topical drug administration can control the occurrence and development of early caries.This paper comprehensively reviewed the action principle,anti-caries effect and clinical application of topical drug administration in early caries from the three aspects,including fluoride and fluoride containing formulations,antibiotics and natural active ingredients,by retrieving the databases at home and abroad,aimed at strengthening the awareness of the caries hazard and importance of topical drug administration for prevention and treatment of early caries,and providing certain references for clinic.
作者
宋洁
吴泽钰(综述)
赵今(审校)
SONG Jie;WU Zeyu;ZHAO Jin(Department of Dentistry and Endodontics,Affiliated Stomatological Hospital,the First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830054,China;Institute of Stomatology of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830054,China)
出处
《重庆医学》
CAS
2022年第20期3578-3582,共5页
Chongqing medicine
基金
口腔疾病研究国家重点实验室开放课题(SKLOD2021OF04)。
关键词
龋齿
局部用药
防治
综述
dental caries
topical drug administration
prevention and treatment
review
