摘要
脱髓鞘假瘤(demyelinating pseudotumor,DPT)是一种中枢神经系统炎性脱髓鞘疾病,以脱髓鞘为主要病理改变,在临床上少见。1例24岁系统性红斑狼疮女性患者,因“双下肢麻木伴乏力”入院,头颅MRI提示颅内多发占位性病变,最终考虑DPT。经甲泼尼龙冲击治疗和环磷酰胺免疫抑制剂治疗后,患者症状明显好转。系统性红斑狼疮伴DPT极为罕见,应注意与其他神经精神型红斑狼疮和颅内肿瘤等疾病相鉴别,以避免不必要的有创操作和治疗。
Demyelinating pseudotumor(DPT)is an inflammatory demyelinating disease in central nervous system,and the main pathological change is demyelination,which is rare in clinical practice.A 24-year-old female patient with systemic lupus erythematosus was admitted to our hospital with the chief complaint of bilateral lower limb numbness and fatigue.Brain MRI observed the bilateral,multiple space-occupying lesions in the brain.Thus she was diagnosed as DPT.After the treatment with prednisolone and cyclophosphamide,the above-mentioned symptoms were significantly improved.The systemic lupus erythematosus combined with the DPT is rare,which should be differentiated from other neuropsychiatric diseases(such as lupus erythematosus and intracranial tumor)and avoid unnecessary invasive procedures and treatment.
作者
陈影
李丽雅
桂明
CHEN Ying;LI Liya;GUI Ming(Department of Rheumatology,Third Xiangya Hospital,Central South University,Changsha 410013,China)
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2022年第9期1299-1302,共4页
Journal of Central South University ：Medical Science
关键词
系统性红斑狼疮
脱髓鞘假瘤
免疫
systemic lupus erythematosus
demyelinating pseudotumor
immune
